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Displaying results 4721 - 4730 of 9670 in total
  1. Drug

    Gaboxadol

    go.drugbank.com/drugs/DB06554
    Investigational

    Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives. … Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing

  2. Drug

    Gantenerumab

    go.drugbank.com/drugs/DB12034
    Investigational

    [solanezumab], which are at varying stages of clinical development. … [A244705, A244710] These treatments include the related antibodies [aducanumab], which has been granted accelerated FDA approval, along with [bapineuzumab], [crenezumab], [donanemab], [lecanemab], and

  3. Drug

    Fluoroacetic acid F-18

    go.drugbank.com/drugs/DB15202
    Investigational

    Fluoroacetic acid F-18 is under investigation in clinical trial NCT01320787 (18-F-Fluoroacetate as PET Imaging Agent).

  4. Drug

    (5Z,7E,9)-decatrien-2-one

    go.drugbank.com/drugs/DB15619
    Investigational

    Similar to [(5E,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116]

  5. Drug

    BIIB015

    go.drugbank.com/drugs/DB06304
    Investigational

    It has been investigated for the treatment of subjects with relapsed or refractory solid tumours.

  6. Drug

    Cefmenoxime

    go.drugbank.com/drugs/DB00267
    Approved

    It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.

    Synonyms: (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure
  7. Drug

    Gliquidone

    go.drugbank.com/drugs/DB01251
    Approved

    It is an ATP-dependent K+ (KATP) channel blocker.

    Products: GLURENORM 30MG TABLETTE, GLURENOR 30MG TABLETTEN
  8. Drug

    Leukotriene C4

    go.drugbank.com/drugs/DB08855
    Experimental

    It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. … It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)

    Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine
  9. Drug

    DTS-201

    go.drugbank.com/drugs/DB06071
    Experimental

    It is activated in the tumor environment. … solid tumors, including tumors sensitive to doxorubicin and potentially other tumors which are not currently treated with doxorubicin but which express high levels of CD-10* or TOP** peptidases, such as

  10. Drug

    Sulopenem

    go.drugbank.com/drugs/DB15284
    Investigational

    It is marketed as the prodrug [sulopenem etzadroxil] in combination with [probenecid].[L51768]