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Displaying results 4771 - 4780 of 10000 in total
  1. Drug

    Orbofiban

    go.drugbank.com/drugs/DB20676
    Experimental

    Orbofiban has a monoisotopic molecular weight of 361.18 Da. … Orbofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Orbofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  2. Drug

    Gantofiban

    go.drugbank.com/drugs/DB20951
    Experimental

    Gantofiban has a monoisotopic molecular weight of 447.21 Da. … Gantofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  3. Drug

    Roxifiban

    go.drugbank.com/drugs/DB21089
    Experimental

    Roxifiban has a monoisotopic molecular weight of 447.21 Da. … Roxifiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Roxifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  4. Drug

    Sibrafiban

    go.drugbank.com/drugs/DB21420
    Experimental

    Sibrafiban has a monoisotopic molecular weight of 420.2 Da. … Sibrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  5. Drug

    Padoprazan

    go.drugbank.com/drugs/DB21689
    Experimental

    Padoprazan has a monoisotopic molecular weight of 405.12 Da. … Padoprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Padoprazan is a proton pump inhibitor, not dependent on acid activation.

  6. Drug

    Zerencotrep

    go.drugbank.com/drugs/DB21710
    Experimental

    Zerencotrep has a monoisotopic molecular weight of 524.11 Da. … Zerencotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Zerencotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.

  7. Drug

    Loprazolam

    go.drugbank.com/drugs/DB13643
    Experimental

    Loprazolam is recommended as a short-term therapy only, due to adverse events associated with the drug including dependence and withdrawal symptoms. … It is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug.

  8. Drug

    Pexidartinib

    go.drugbank.com/drugs/DB12978
    ApprovedInvestigational

    [A182240,L7901] Debilitating symptoms often follow with tenosynovial giant cell tumors, along with a risk of significant functional limitations and a reduced quality of life in patients. … [L7901] While surgical resection is a current standard of care for tenosynovial giant cell tumor, there are tumor types where surgeries are deemed clinically ineffective with a high risk of lifetime

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  9. Drug

    Pleconaril

    go.drugbank.com/drugs/DB05105
    Investigational

    Food and Drug Administration (FDA) due to the fact that it has been found to induce CYP3A enzyme activity, therefore increasing the risk for serious drug interactions. … Pleconaril is an antiviral drug from _viral capsid inhibitor_ class, manufactured by _Schering-Plough_ and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic

  10. Drug

    Meprobamate

    go.drugbank.com/drugs/DB00371
    ApprovedIllicit

    A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Meprobamate is a controlled substance in the U.S.