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Displaying results 471 - 480 of 5876 in total
  1. Drug

    Nemolizumab

    go.drugbank.com/drugs/DB15252
    ApprovedInvestigational

    [A264254] By binding to IL-31RA, nemolizumab blocks the IL-31 signalling cascades that lead to inflammation.

  2. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    in response to oxidative stress. … It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated

  3. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affe...

    Mixtures: Kisqali Femara Co-pack, Kisqali Femara Co-packProducts: Co Letrozole, LETROZOLO DOC GENERICI
  4. Drug

    Carvedilol

    go.drugbank.com/drugs/DB01136
    ApprovedInvestigational

    [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension. … [L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the

    Synonyms: (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanolMixtures: Co-Dilatrend 25 mg/12,5 mg - Filmtabletten
  5. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    In human muscle, urate is oxidized to allantoin during such exercise [FDA Label]. … Allantoin has also demonstrated to ameliorate the wound healing process in some studies [A23498].

    Mixtures: Mycellcare All in One Serum, Skinbutak Go Young Magic TonerProducts: W-Care, YES to coconut
  6. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. … [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  7. Drug

    Trastuzumab

    go.drugbank.com/drugs/DB00072
    ApprovedInvestigational

    It displays biosimilar properties as Herceptin according to clinical data. … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and indirectly [A121].

  8. Drug

    Capsicum oleoresin

    go.drugbank.com/drugs/DB11131
    Approved

    Due to its analgesic properties, capsicum oleoresin is used to temporarily relieve of minor aches and pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied

    Mixtures: Herbalax Forte No 70 Tab, HO YAN HOR MEDICATED OIL
  9. Drug

    Neon

    go.drugbank.com/drugs/DB11589
    Approved

    Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic. It is the fifth most abundant chemical element in the universe by mass but a rare element on E...

    Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 Mixture
  10. Drug

    Lomitapide

    go.drugbank.com/drugs/DB08827
    Approved

    [A275445, A7367] This makes it a critical therapeutic option for "receptor-negative" patients who have little to no functional LDL receptor activity. … [A7367] Lomitapide was first approved by the FDA in December 2012 and the EMA in July 2013 as an adjunct to a low-fat diet and other lipid-lowering treatments.[A275444, A275446]