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Displaying results 4801 - 4810 of 10000 in total
  1. Drug

    Regramostim

    go.drugbank.com/drugs/DB05386
    Investigational

    Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. … Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages.

    Synonyms: Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107, GM-CSF (CHO cell)
  2. Drug

    Atropine

    go.drugbank.com/drugs/DB00572
    ApprovedInvestigationalVet approved

    It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. … [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods.

    Mixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML, Me-PB-HyosCategories: P-glycoprotein substrates
  3. Drug

    Geraniol

    go.drugbank.com/drugs/DB14183
    Approved

    Sensitivity to geraniol may be identified with a clinical patch test. … Due to its anticancer effects, geraniol has been found to be effective against a broad range of cancers including breast, lung, colon, prostate, pancreatic, skin, liver, kidney and oral cancers [A34262

    Synonyms: 2-trans-3,7-Dimethyl-2,6-octadien-1-ol, (2E)-3,7-dimethylocta-2,6-dien-1-ol
  4. Drug

    N,N-dimethylarginine

    go.drugbank.com/drugs/DB01686
    Experimental

    ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. … It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid.

    Synonyms: N(5)-((Dimethylamino)iminomethyl)-L-ornithine, L-NG,NG-dimethylarginine
  5. Drug

    BG-P-TAT

    go.drugbank.com/drugs/DB18105
    Experimental

    Synonyms: 2-(4-(4-((1-(107-(4-(guanidinomethyl)phenoxy)-(polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid
  6. Drug

    EP-0042

    go.drugbank.com/drugs/DB18120
    Investigational

    Synonyms: 3H-IMIDAZO(4,5-B)PYRIDINE, 6-CHLORO-7-(4-((4-CHLOROPHENYL)METHYL)-1-PIPERAZINYL)-2-(1,3-DIMETHYL-1H-PYRAZOL-4-YL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    3'-beta-Sialyl-beta-lactose

    go.drugbank.com/drugs/DB03296
    Experimental

    Synonyms: O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose, 3'-beta-Sialyl-beta-lactose
  8. Drug

    Bomedemstat

    go.drugbank.com/drugs/DB17234
    Investigational

    Synonyms: IMG-7289, Benzamide, n-((1s)-4-(((1r,2s)-2-(4-fluorophenyl)cyclopropyl)amino)-1-((4-methyl-1-piperazinyl)carbonyl)butyl)-4-(1h-1,2,3-triazol-1-yl)-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Tomaralimab

    go.drugbank.com/drugs/DB15415
    Investigational

    Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).

    Synonyms: Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion tissue injuryCategories: Immunoglobulin G
  10. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

    Synonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)