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Topiroxostat
go.drugbank.com/drugs/DB01685InvestigationalXanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. … Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.
Nadifloxacin
go.drugbank.com/drugs/DB12447InvestigationalNadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
Categories: Antiinfectives for Treatment of AcneBeclabuvir
go.drugbank.com/drugs/DB12225InvestigationalBeclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
Categories: Antivirals for treatment of HCV infectionsPhytochlorin
go.drugbank.com/drugs/DB19265InvestigationalPhytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(pdt) With Chlorin-e6 in Treating Moderate to Severe Acne
Categories: Heterocyclic Compounds with 4 or More RingsAjmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnAn alkaloid found in the root of Rauwolfia serpentina, among other plant sources. … It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope.
Abt-925 anhydrous free base
go.drugbank.com/drugs/DB33803InvestigationalCategories: Receptors, Dopamine D3, antagonists & inhibitorsOxantel
go.drugbank.com/drugs/DB13670InvestigationalOxantel is an anthelmintic drug that targets parasitic acetylcholine receptors.[A275093, A275098]
Mixtures: PAMOATO DE PIRANTEL/PAMOATO DE OXANTEL SUSPENSION, PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN.CR665
go.drugbank.com/drugs/DB05155ExperimentalIn addition, unlike currently marketed opioids, CR665 does not produce inhibition of intestinal transit (ileus), induce respiratory depression, or elicit signs of euphoria or addiction in animal models … CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists.
Iodine povacrylex
go.drugbank.com/drugs/DB09537ApprovedProlonged skin exposure could cause skin defatting manifested by the following signs/symptoms; localized redness, itching, drying and cracking of skin. … DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the preparation of the skin prior to surgery and to help reduce bacteria that can potentially cause skin infection
Dextromoramide
go.drugbank.com/drugs/DB01529ExperimentalIllicitAn opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: D-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine