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Haloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigational[F4645] It is also used off-label for the management of chorea associated with Huntington's disease and for the treatment of intractable hiccups as it is a potent antiemetic. … However, this class of drugs is also limited by the development of movement disorders induced by dopamine-blockade such as drug-induced parkinsonism, akathisia, dystonia, tardive dyskinesia, as well as
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-oneTridihexethyl
go.drugbank.com/drugs/DB00505ApprovedWithdrawnTridihexethyl is an antimuscarinic, anticholinergic drug. Tridihexethyl is no longer available in the US market. … Tridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
Dextrothyroxine
go.drugbank.com/drugs/DB00509ApprovedWithdrawnThyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism. … Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood.
Synonyms: O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine, D-thyroxineCinchocaine
go.drugbank.com/drugs/DB00527ApprovedVet approvedA local anesthetic of the amide type now generally used for surface anesthesia. … It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Mixtures: Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5%, ULTRAPROCT %0,09+%0,09+%0,5 MERHEM, 10 GCategories: Heterocyclic Compounds, 2-RingFoscarnet
go.drugbank.com/drugs/DB00529ApprovedInvestigationalAn antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Erlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalRecent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … It is typically marketed under the trade name Tarceva.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amineCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, a...
Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideEtofenamate
go.drugbank.com/drugs/DB08984InvestigationalEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
Mixtures: THERMO RHEUMON 100 MG/G + 10 MG/G KREM, 50 G, THERMOFLEX %10 + %1 KREM, 50 GCategories: Non COX-2 selective NSAIDSEtidocaine
go.drugbank.com/drugs/DB08987ApprovedEtidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. … Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.
Eprazinone
go.drugbank.com/drugs/DB08990ApprovedWithdrawnEprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.