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Displaying results 4861 - 4870 of 10000 in total
  1. Drug

    Cobamamide

    go.drugbank.com/drugs/DB11191
    ApprovedNutraceutical

    The principal biochemical participants are two coenzyme forms of Vitamin B12 that are produced and activated in two separate cellular compartments: methylcobalamin in the cytosol and adenosylcobalamin … MeCbl is mainly involved along with folate in hematopoiesis and the growth of the brain during childhood.

    Mixtures: EnLyte Extra-LNCategories: Enzymes and Coenzymes, Blood and Blood Forming Organs
  2. Drug

    Vecabrutinib

    go.drugbank.com/drugs/DB16657
    Investigational

    Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).

  3. Drug

    MK-0533

    go.drugbank.com/drugs/DB15242
    Investigational

    MK-0533 is under investigation in clinical trial NCT00543959 (Efficacy and Tolerability of MK0533 in Patients With Type 2 Diabetes (0533-005)).

  4. Drug

    ATB-346

    go.drugbank.com/drugs/DB15377
    Investigational

    ATB-346 is under investigation in clinical trial NCT03220633 (Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects).

  5. Drug

    Plozalizumab

    go.drugbank.com/drugs/DB12520
    Investigational

    Preclinical studies suggest that CCR2 plays an important role in the trafficking of monocytes and macrophages to sites of inflammation. … The recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis.

    Categories: Amino Acids, Peptides, and Proteins
  6. Drug

    Nickel sulfate

    go.drugbank.com/drugs/DB14180
    Approved

    Nickel sulfate is used in allergenic testing.

    Mixtures: Multivitamins and Minerals Tablets, Milltrium Senior Vitamin and Mineral SupplementCategories: Compounds used in a research, industrial, or household setting
  7. Indication

    Joint Diseases

    go.drugbank.com/conditions/DBCOND0028263
    Drugs: Thymol
    Synonyms: Osteoarthritis and allied disorders
  8. Drug

    MK-0873

    go.drugbank.com/drugs/DB13029
    Investigational

    MK-0873 has been used in trials studying the treatment of Rheumatoid Arthritis.

  9. Drug

    Albinterferon Alfa-2B

    go.drugbank.com/drugs/DB05396
    Investigational

    In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they ceased development of the drug. … The drug was under investigation as an alternative to pegylated IFN-α-2a for the treatment of hepatitis C.

    Categories: Interferon Type I, Amino Acids, Peptides, and ProteinsSynonyms: alb-IFN
  10. Drug

    Odronextamab

    go.drugbank.com/drugs/DB16684
    ApprovedInvestigational

    [A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can lead to the development … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, Regeneron Pharmaceuticals, to amend clinical protocols to reduce the incidence of CRS.

    Categories: Antineoplastic and Immunomodulating Agents, Monoclonal antibodies and antibody drug conjugates