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Displaying results 4871 - 4880 of 10000 in total
  1. Drug

    Sodium sulfide

    go.drugbank.com/drugs/DB11159
    Approved

    Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dyes and oil … However the clinical significance and mechanism of action of sodium sulfide and replication of results across other studies are not yet fully determined.

  2. Drug

    Liposomal prostaglandin E1

    go.drugbank.com/drugs/DB05391
    Investigational

    The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways that PGE-1 alone could not achieve. … Liposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent.

  3. Drug

    Fasinumab

    go.drugbank.com/drugs/DB12157
    Investigational

    [A241165] NGF was first discovered in the 1950s[A241180] and was the first neurotrophic factor to be identified and biochemically characterized. … It is currently under investigation for the treatment osteoarthritic pain[A241045] and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy (i.e

  4. Drug

    Brofaromine

    go.drugbank.com/drugs/DB13876
    Experimental

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    2,5-Dimethoxy-4-ethylthioamphetamine

    go.drugbank.com/drugs/DB13940
    Experimental

    2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor Agonists
  6. Drug

    AdPEDF

    go.drugbank.com/drugs/DB05138
    Experimental

    It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors … AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD).

  7. Drug

    Aceprometazine

    go.drugbank.com/drugs/DB01615
    Experimental

    Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.

  8. Drug

    IMM101

    go.drugbank.com/drugs/DB15851
    Experimental

    Studies with IMM-101 showed the vaccine’s ability to stimulate cancer patients’ immune systems to help kill cancer cells. … It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma [PMID: 21930686; PMID: 30107850; PMID: 27599039].

  9. Target

    Kinesin-like protein KIF11

    go.drugbank.com/bio_entities/BE0001852
    TargetHumans

    Motor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis (PubMed:19001501, PubMed:37728657). Required in non-mitotic cells for transport of secretory proteins from the Golgi...

    Synonyms: Thyroid receptor-interacting protein 5
  10. Drug

    Faropenem medoxomil

    go.drugbank.com/drugs/DB05659
    Investigational

    The prodrug form of faropenem offers dramatically improved oral bioavailability and leads to higher systemic concentrations of the drug. … Faropenem medoxomil is an ester prodrug derivative of the beta-lactam antibiotic [faropenem].