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Displaying results 4871 - 4880 of 10000 in total
  1. Pathway

    De Novo Triacylglycerol Biosynthesis TG(22:4(7Z,10Z,13Z,16Z)/20:0/22:4(7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0025251
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  2. Pathway

    Acylcarnitine (2E,6E,10E)-Pentadeca-2,6,10-trienedioylcarnitine

    smpdb.ca/view/SMP0124246
    Metabolic

    (2E,6E,10E)-Pentadeca-2,6,10-trienedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2E,6E,10E)-pentadeca-2,6,10-trienedioyl-CoA reacts with L-carnitine to form (2E,6E,10E)-pentadeca-2,6,10-trienedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Pathway

    Acylcarnitine (6Z,10Z,14Z)-hexadeca-6,10,14-trienoylcarnitine

    smpdb.ca/view/SMP0124291
    Metabolic

    (6Z,10Z,14Z)-hexadeca-6,10,14-trienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA reacts with L-carnitine to form (6Z,10Z,14Z)-hexadeca-6,10,14-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Pathway

    Acylcarnitine (10E,12Z)-9-hydroxyoctadeca-10,12-dienoylcarnitine

    smpdb.ca/view/SMP0124341
    Metabolic

    (10E,12Z)-9-hydroxyoctadeca-10,12-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10E,12Z)-9-hydroxyoctadeca-10,12-dienoyl-CoA reacts with L-carnitine to form (10E,12Z)-9-hydroxyoctadeca-10,12-dienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  5. Pathway

    Acylcarnitine (7Z,10Z,13E)-docosa-7,10,13-trienoylcarnitine

    smpdb.ca/view/SMP0124398
    Metabolic

    (7Z,10Z,13E)-docosa-7,10,13-trienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (7Z,10Z,13E)-docosa-7,10,13-trienoyl-CoA reacts with L-carnitine to form (7Z,10Z,13E)-docosa-7,10,13-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  6. Drug

    Lurbinectedin

    go.drugbank.com/drugs/DB12674
    ApprovedInvestigational

    Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer, … Ecteinascidia turbinata_, with the primary difference being the substitution of the tetrahydroisoquinoline with a tetrahydro β‐carboline that results in increased antitumour activity of lurbinectedin as

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ZEPZELCA POWDER FOR SOLUTION FOR INFUSION 4MG/VIAL
  7. Drug

    Lobeglitazone

    go.drugbank.com/drugs/DB09198
    Investigational

    It primarily functions as an insulin sensitizer by binding and activating Peroxisome Proliferator-Activated Receptors (PPAR) gamma within fat cells. … Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  8. Pathway

    Acylcarnitine (6E,10E)-3-Hydroxydodeca-6,10-dienoylcarnitine

    smpdb.ca/view/SMP0124044
    Metabolic

    (6E,10E)-3-Hydroxydodeca-6,10-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (6E,10E)-3-hydroxydodeca-6,10-dienoyl-CoA reacts with L-carnitine to form (6E,10E)-3-hydroxydodeca-6,10-dienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  9. Pathway

    Acylcarnitine (4E,7E,10E)-hexadeca-4,7,10-trienoylcarnitine

    smpdb.ca/view/SMP0124288
    Metabolic

    (4E,7E,10E)-hexadeca-4,7,10-trienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA reacts with L-carnitine to form (4E,7E,10E)-hexadeca-4,7,10-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Pathway

    Acylcarnitine (4E,7E,10E)-hexadeca-4,7,10-trienedioylcarnitine

    smpdb.ca/view/SMP0124292
    Metabolic

    (4E,7E,10E)-hexadeca-4,7,10-trienedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (4E,7E,10E)-hexadeca-4,7,10-trienedioyl-CoA reacts with L-carnitine to form (4E,7E,10E)-hexadeca-4,7,10-trienedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more