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Montelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationala generic and as a brand name product. … Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersProducts: MONK-P, Ag-montelukastEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ENTECAVIR AL 1MG, ENTECAVIR AL 0.5MGLevofloxacin
go.drugbank.com/drugs/DB01137ApprovedInvestigational[L11638] Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin].
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Ava-levofloxacin, LEVOFLOXACIN AL 250MG FTAMomelotinib
go.drugbank.com/drugs/DB11763ApprovedInvestigationalMF includes primary MF (PMF), post-polycythemia vera (PV) MF, and post-essential thrombocythemia (ET) MF. Clinical manifestations of MF include anemia and thrombocytosis. … Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigationalMycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). … It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Ag-mycophenolate, CELLCEPT 500 MG IV İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ, 4 ADETToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigational[L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor. … The proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsZinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Mixtures: Zincfrin A, One-A-day Advance Men'sProducts: SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE., ZINK AL 25MG BRAUSETABLCefpodoxime
go.drugbank.com/drugs/DB01416ApprovedInvestigationalVet approvedCefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. … Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Products: CEFPODOXIM AL 100MG, CEFPODOXIM AL 200MGTolperisone
go.drugbank.com/drugs/DB06264InvestigationalIt possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. … Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: TOLPERISONHCL AL 50MG, TOLPERISONHCL AL 150MGTriclosan
go.drugbank.com/drugs/DB08604ApprovedAn aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards
Mixtures: First Aid Antiseptic Well at Walgreens, QV FLARE UP BATH OILProducts: PF Anti Bac, A-Septic AS Gel