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Displaying results 481 - 490 of 10000 in total
  1. Drug

    Prasterone sulfate

    go.drugbank.com/drugs/DB05804
    Investigational

    DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.

    Categories: Cytochrome P-450 CYP3A7 SubstratesSynonyms: (3-beta)-3-(Sulfooxy)androst-5-en-17-one, 3beta-Hydroxyandrost-5-en-17-one 3-sulfate
  2. Drug

    4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07685
    Experimental

    Synonyms: 4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
  3. Drug

    3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine

    go.drugbank.com/drugs/DB08533
    Experimental

    Synonyms: 3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine
  4. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].

    Mixtures: Hands First 4 in 1, NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 GCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE

    go.drugbank.com/drugs/DB08345
    Experimental

    Synonyms: 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  6. Drug

    Ezogabine

    go.drugbank.com/drugs/DB04953
    ApprovedWithdrawn

    It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures … Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine.

    Synonyms: N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester, N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester
  7. Drug

    Alfentanil

    go.drugbank.com/drugs/DB00802
    ApprovedIllicitInvestigational

    A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. … Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilide
  8. Drug

    Cinnarizine

    go.drugbank.com/drugs/DB00568
    ApprovedInvestigational

    Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. … Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting

    Mixtures: Arlevert 20 mg/40 mg TablettenCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  9. Drug

    Hydroxyamphetamine

    go.drugbank.com/drugs/DB09352
    Approved

    Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. … stinging in the eyes.

    Synonyms: 4-(2-aminopropyl)phenol, 4-hydroxyamphetamine
  10. Drug

    2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide

    go.drugbank.com/drugs/DB08026
    Experimental

    Synonyms: 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide