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Estramustine phosphate
go.drugbank.com/drugs/DB14674ApprovedA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Cyanocobalamin Co-60
go.drugbank.com/drugs/DB09387ApprovedWithdrawnCyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons. … Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60.
Lufotrelvir
go.drugbank.com/drugs/DB16514InvestigationalPF-07304814 is a small molecule prodrug that targets the 3CL<sup>pro</sup> protease (M<sup>pro)</sup>, which is used by viruses like SARS-CoV-2 to assemble and multiply[L31718]. … Once administered through intravenous infusion, the compound is cleaved into PF-00835231 to exert its anti-viral effects[L31718].
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRivanicline
go.drugbank.com/drugs/DB05855ExperimentalRivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. … It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8.
Categories: Heterocyclic Compounds, 1-RingSynonyms: (E)-metanicotine, (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amineINKP-102
go.drugbank.com/drugs/DB05326ExperimentalINKP-102 is the next generation sodium phosphate tablet designed to aid bowl preparation before colonoscopy.
Sulfamoxole
go.drugbank.com/drugs/DB08798ExperimentalSulfamoxole is an antibacterial in the sulfonamide class.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: N(sup 1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide, 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamideRindopepimut
go.drugbank.com/drugs/DB05374InvestigationalThe vaccine consists of the EGFRv3-specific peptide (a 13-amino acid mutant vIII epitope) conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH). … The US FDA granted it Breakthrough Therapy Designation for glioblastoma in Feb 2015.
Ulotaront
go.drugbank.com/drugs/DB15665InvestigationalUnlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5 … SEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesFenbendazole
go.drugbank.com/drugs/DB11410InvestigationalVet approvedFenbendazole is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs, cats, rabbits and seals. … It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and
Synonyms: 2-(methoxycarbonylamino)-5-(phenylthio)benzimidazole, methyl 5-(phenylthio)-2-benzimidazolecarbamateCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingCorticorelin
go.drugbank.com/drugs/DB05394InvestigationalCorticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone, also called hCRF.