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Tacrine
go.drugbank.com/drugs/DB00382ApprovedWithdrawnA centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous
Ethyl methoxycinnamate
go.drugbank.com/drugs/DB16440InvestigationalSynonyms: Ethyl (E)-4-methoxycinnamate, Ethyl (E)-p-methoxycinnamateMixtures: SPF 50Vesnarinone
go.drugbank.com/drugs/DB12082InvestigationalVesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Categories: Compounds used in a research, industrial, or household settingPropacetamol
go.drugbank.com/drugs/DB09288Investigational[A32051] It is a derivative of [acetaminophen], or paracetamol, with the molecular formula glycine, N, N-diethyl-,4-(acetylamino)phenyl ester. … [A7892] It is not available in the United States but this prodrug has been widely used in other countries such as France since 1985.[L1505]
Acteoside
go.drugbank.com/drugs/DB12996InvestigationalActeoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy).
Categories: Compounds used in a research, industrial, or household settingAdrenomedullin
go.drugbank.com/drugs/DB19102InvestigationalAdrenomedullin is under investigation in clinical trial NCT06072118 (Adrenomedullin for CADASIL).
Categories: Compounds used in a research, industrial, or household settingGeneral transcription and DNA repair factor IIH helicase/translocase subunit XPB
go.drugbank.com/bio_entities/BE0012820TargetHumansComponent of the general transcription and DNA repair factor IIH (TFIIH) core complex (PubMed:10024882, PubMed:17466626, PubMed:8157004, PubMed:8465201). … The structure of the TFIIH transcription complex differs from the NER-TFIIH complex; large movements by XPD/ERCC2 and XPB/ERCC3 are stabilized by XPA (PubMed:31253769, PubMed:33902107).
Synonyms: TFIIH basal transcription factor complex 89 kDa subunitMetrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Categories: Compounds used in a research, industrial, or household settingMersalyl
go.drugbank.com/drugs/DB09338ExperimentalInterestingly, it has been found to have antiviral properties in mice [L1584]. … It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577].
Cilansetron
go.drugbank.com/drugs/DB04885ExperimentalCilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase in the EU and US.