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Clozapine Serotonin Antagonist Action Pathway
smpdb.ca/view/SMP0125311Drug actionClozapine is an antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. Clozapine is available as oral tablets. Clozapine is part of a group of drugs known as second-generation...
Aripiprazole Serotonin Agonist Action Pathway
smpdb.ca/view/SMP0126456Drug actionAripiprazole is an atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome....
Ziprasidone Serotonin Action Action Pathway
smpdb.ca/view/SMP0126471Drug actionZiprasidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and acute agitation in schizophrenic patients. It also indicated improvement on the manic syndrome subscale that measures symptoms of mania such as mood...
Escitalopram Mechanism of Action Action Pathway New
smpdb.ca/view/SMP0126509Drug actionEscitalopram is the therapeutic active S- enantiomer of citalopram. It is classified as a selective serotonin reuptake inhibitor used to treat depression and anxiety. It's mechanism of action it to bind selectively bind to the sodium dep...
Fluvoxamine Mechanism of Action Action Pathway New
smpdb.ca/view/SMP0126511Drug actionFluvoxamine, an aralkylketone-derivative agent, is one of a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) that differs structurally from other SSRIs. It is used to treat the depression associated with ...
Flupentixol Serotonin Antagonist Action Pathway
smpdb.ca/view/SMP0126516Drug actionFlupentixol is a first generation antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in i...
Paliperidone Serotonin Antagonist Action Pathway
smpdb.ca/view/SMP0126597Drug actionPaliperidone is the primary active metabolite of risperidone. The two antipsychotics are also metabolized differently, as risperidone is metabolized in the liver mainly by the polymorphic cytochrome P450 2D6 (CYP2D6) to its active metabo...
Amitriptyline Serotonin Antagonist Action Pathway
smpdb.ca/view/SMP0126617Drug actionAmitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. The non-FDA-approved indications are anxiety, post-traumatic stre...
Lumateperone SSRI Action Action Pathway
smpdb.ca/view/SMP0126693Drug actionLumateperone, also known as ITI-007, is approved for the treatment of schizophrenia in adults. It is also approved for the treatment of depressive episodes associated with bipolar disorder (i.e. bipolar depression) in adults, as monother...
Lumateperone Serotonin Antagonist Action Pathway
smpdb.ca/view/SMP0126695Drug actionLumateperone, also known as ITI-007, is approved for the treatment of schizophrenia in adults. It is also approved for the treatment of depressive episodes associated with bipolar disorder (i.e. bipolar depression) in adults, as monother...