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Digoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigationalDigoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: LANOXIN PG 62.5MCG TABLETS, LANOXIN-PG PAEDIATRIC/GERIATRIC TABLET 0.0625 mgDoxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigationalDoxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasti...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: CARDULAR PP 4MG, CARDULAR PP 8MGDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Cosopt PF, Cosopt PFCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymb...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: XERISTAR 30MG KAP MAGENSAF, XERISTAR 60MG KAP MAGENSAFNitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing...
Products: H0-P3Rivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Ixobran 15 (Rivaroxaban Tablet Ph Eur 15mg), Ixobran 10 (Rivaroxaban Tablet Ph Eur 10mg)Naphazoline
go.drugbank.com/drugs/DB06711ApprovedNaphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles . It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations . Naphazoline was firs...
Products: Pi Yen Chin, Pi Yuan ChinRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 b...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: REQUIP PD 24 HOUR, REQUIP PD 24 HOUR 2mg Prolonged Release TabletsPropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: Hydration PF, Systane Hydration PF Preservative FreeProducts: Systane COMPLETE PFNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approvedNeomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framyce...
Mixtures: KRIM PI KANG SHUANG, PS-2261 Triple Antibiotic, 0.5gProducts: NEOMYCIN PF-50% W/W POWDER