Search
Dacarbazine
go.drugbank.com/drugs/DB00851ApprovedInvestigationalAn antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamideAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Synonyms: 5-(propylthio)-2-carbomethoxyaminobenzimidazole, O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamateInternational brands: Ben-AAdenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 5'-AMP, Adenosine-5'PFlavin adenine dinucleotide
go.drugbank.com/drugs/DB03147ApprovedA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase.
Categories: Heterocyclic Compounds, 3-Ring, Vitamin B ComplexSynonyms: adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate], Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavineMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAlthough demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation
Synonyms: 5-ASA, m-Aminosalicylic acidProducts: VERALAZİN 4 G/100 ML REKTAL SÜSPANSİYON, 7 ADET, 5-asaSulfisoxazole
go.drugbank.com/drugs/DB00263ApprovedVet approvedA short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Synonyms: 3,4-Dimethyl-5-sulfanilamidoisoxazole, 3,4-Dimethyl-5-sulfonamidoisoxazoleCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsButalbital
go.drugbank.com/drugs/DB00241ApprovedIllicitButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index.
Synonyms: 5-allyl-5-isobutyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-(2-methylpropyl)barbituric acidMixtures: Butalbital and Acetaminophen 50 mg/325 mg, Fiorinal-C 1/4Carbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigational[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.
Categories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP1A2 InducersSynonyms: 5-Carbamoyl-5H-dibenz(b,f)azepine, 5-carbamoyl-5H-dibenz[b,f]azepineFloxuridine
go.drugbank.com/drugs/DB00322ApprovedInvestigationalFloxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 5-FUdR, 2'-Deoxy-5-fluorouridineLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Synonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates