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Displaying results 491 - 500 of 9192 in total
  1. Drug

    Inclisiran

    go.drugbank.com/drugs/DB14901
    ApprovedInvestigational

    By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. … [L28178] Inclisiran was later approved by the FDA on December 22, 2021, for the treatment of heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease in adults

    Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, Sybrava 284mg/1.5ml Solution for Injection in Pre-filled Syringe
  2. Drug

    Eravacycline

    go.drugbank.com/drugs/DB12329
    ApprovedInvestigational

    Eravacycline has demonstrated superior potency to that of antibiotics that are currently being marketed for intraabdominal infections [A38727]. … It was first approved by the FDA on August 27, 2018 [L4540].

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIAL
  3. Drug

    Erenumab

    go.drugbank.com/drugs/DB14039
    ApprovedInvestigational

    Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only FDA approved treatment specifically developed to prevent migraine by blocking the … Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines

    Products: AIMOVIG (140 MG/ML SOLUTION FOR INJECTION), AIMOVIG (70 MG/ML SOLUTION FOR INJECTION)
  4. Drug

    Clofarabine

    go.drugbank.com/drugs/DB00631
    ApprovedInvestigational

    Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand.

    Products: EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for Infusion
  5. Drug

    Epirubicin

    go.drugbank.com/drugs/DB00445
    ApprovedInvestigational

    The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

    Products: EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg, EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mg
  6. Drug

    Hypochlorous acid

    go.drugbank.com/drugs/DB14135
    Investigational

    An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

    Categories: Compounds used in a research, industrial, or household settingProducts: Disinfectant Solution for air, Disinfectant Solution for hand-use
  7. Drug

    Mosunetuzumab

    go.drugbank.com/drugs/DB15434
    ApprovedInvestigational

    [L44562] and in December 2025, the subcutaneous formulation was approved for the same indication. [L54848] … [L42245] In June 2022, the European Medicines Agency approved mosunetuzumab for the treatment of adult patients with relapsed or refractory (R/R) FL who have received at least two prior systemic therapies

    Products: Lunsumio 1mg/ml Concentrate for Solution for Infusion
  8. Indication

    Born to a mother who is RT-PCR for Zaire ebolavirus

    go.drugbank.com/conditions/DBCOND0135806
    Drugs: Ansuvimab
    Synonyms: Born to a mother who is RT-PCR for Zaire ebolavirus
  9. Indication

    When unable to prescribe first line therapy for streptococcus pyogenes pharyngitis

    go.drugbank.com/conditions/DBCOND0117147
    Drugs: Azithromycin
    Synonyms: When unable to prescribe first line therapy for streptococcus pyogenes pharyngitis
  10. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    As patients with haemophilia A are predisposed to episodes of recurrent bleeding [L1115], simoctocog alfa can be administered for the treatment or prevention of bleeding such as prior to surgical procedures … The harvested product is concentrated and purified by a series of chromatography steps.

    Products: Nuwiq 250IU Powder for Solution for Injection, Nuwiq 500IU Powder for Solution for Injection