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Capecitabine
go.drugbank.com/drugs/DB01101ApprovedInvestigationalCapecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, wh...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamatePancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigational[L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.
Mixtures: PANLIPAZ 170/80 MG ENTERİK KAPLI FİLM TABLET, 20 ADET, PANLIPAZ 170/80 MG ENTERİK KAPLI FİLM TABLET, 60 ADETProducts: FESTAL N 220 MG ENTERİK KAPLI TABLET, 50 ADET, KREON KAPSUL 25000 300 MG 100 KAPSULTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of
Synonyms: 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamineMixtures: METOPRIM 200 MG + 40 MG/5 ML SUSPANSIYON, 100 ML, SEPTRIN IV 5 ML 10 AMPULDisopyramide
go.drugbank.com/drugs/DB00280ApprovedInvestigationalA class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NORPACE 100 MG KAPSÜL, 50 ADET, NORPACE 100 MG KAPSÜL, 100 ADETChlorprothixene
go.drugbank.com/drugs/DB01239ApprovedInvestigationalWithdrawnChlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: Truxal 50 mg - Filmtabletten, CHLORPROTHIXEN-NEURAX 100Mefenamic acid
go.drugbank.com/drugs/DB00784ApprovedA non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Mixtures: แอนพัส 520Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsFish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalHowever, prescription-only fish oil products are sometimes prescribed for individuals who demonstrate severe (>= 500 mg/dL) hypertriglyceridemia [FDA Label]. … Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016.
Mixtures: OGAMIX(Evening primrose oil 500 mg, Lecithin oil 500 mg, Fish oil 125 mgand Vitamin E 10 mg Soft Gelatin Capsule), SMOFlipid 200 mg/ml Emulsion zur InfusionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAbrocitinib
go.drugbank.com/drugs/DB14973ApprovedInvestigational[A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy. … JAK inhibitors recently attracted more attention as potential treatments for inflammatory disorders, as JAK inhibition is associated with rapid and sustained anti-inflammatory efects.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: CIBINQO® 50 MG, CİBİNQO 100 MG FİLM KAPLI TABLET, 28 ADETMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigational[A228333] It was approved by the FDA on December 31, 1987, and was marketed under the trademark PRIMACOR® by Sanofi-Aventis US before being discontinued.[L31483] … [A228338, A11759, A228323, A228333, A228348, L31483] Milrinone was originally synthesized at the Sterling Winthrop Research Institute in the 1980s.
Synonyms: 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrileProducts: MILRINONA 10 MG/10 ML, MILRINONA 10 MG/ 10 MLTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalIt was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S.
Synonyms: (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamideProducts: TİGENEX 50 MG İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ, 10 FLAKON, TYGEPOL 50 MG I.V. İNFÜZYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ, 10 ADET