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Displaying results 4991 - 5000 of 10000 in total
  1. Drug

    Taurolidine

    go.drugbank.com/drugs/DB12473
    ApprovedInvestigational

    Antifungal Drugs (LPAD pathway) for the prevention of catheter-related bloodstream infections in a limited and specific patient population. … It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal bacterial infections in patients with peritonitis.

    Categories: Blood Substitutes and Perfusion Solutions
  2. Drug

    Diphemanil

    go.drugbank.com/drugs/DB13720
    ApprovedVet approvedWithdrawn

    Categories: Alimentary Tract and Metabolism, diphemanil and psycholeptics
  3. Drug

    Raltitrexed

    go.drugbank.com/drugs/DB00293
    ApprovedInvestigational

    Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.

    Categories: Antineoplastic and Immunomodulating Agents
  4. Drug

    Xamoterol

    go.drugbank.com/drugs/DB13781
    Approved

    It modulates the sympathetic control of the heart but has no agonist action on β2-adrenoceptors. … Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients.

  5. Drug

    Sodium chlorite

    go.drugbank.com/drugs/DB13210
    Investigational

    Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413]. … Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S.

    Categories: Preparations for Treatment of Wounds and Ulcers
  6. Drug

    Potassium lactate

    go.drugbank.com/drugs/DB09483
    ApprovedWithdrawn

    Mixtures: Ionosol and DextroseCategories: Blood and Blood Forming Organs, Blood Substitutes and Perfusion Solutions
  7. Drug

    Zeranol

    go.drugbank.com/drugs/DB11478
    ExperimentalVet approved

    It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. … It is 3-4x more potent as an estrogen agonist than the related compound zearalenone.

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists
  8. Drug

    Clenoliximab

    go.drugbank.com/drugs/DB06241
    Experimental

    Clenoliximab is a chimeric monoclonal antibody from _Macaca irus_ against CD4 which acts as an immunomodulator. It has investigated for the treatment of rheumatoid arthritis.

    Categories: Amino Acids, Peptides, and Proteins
  9. Drug

    Avapritinib

    go.drugbank.com/drugs/DB15233
    ApprovedInvestigational

    stromal tumors and advanced systemic mastocytosis. … Avapritinib was granted FDA approval on 9 January 2020 [L40363] and EMA approval on 24 September 2020.[L41464]

    Categories: Antineoplastic and Immunomodulating Agents, MATE 2-K Inhibitors
  10. Drug

    IDD-3

    go.drugbank.com/drugs/DB05427
    Experimental

    IDD-3 is a therapeutic specific immunostimulant developed by IDM Pharma in partnership with sanofi-aventis. It consists of mature dendritic cells loaded with lysates from melanoma tumor cell lines. … It includes Dendritophages that are dendritic cells, a type of specialized immune cells derived from the patient's own white blood cells.