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Valganciclovir
go.drugbank.com/drugs/DB01610ApprovedInvestigationalAs the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases. … Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections.
Categories: Heterocyclic Compounds, 2-RingProducts: RUNAVIR®450 MG, VALGOVIR® 450 MGVemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche. … After approval, Roche in collaboration with Genentech launched a broad development program. [L1012]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ZELBORAF ® TABLETAS LACADAS DE 240 MG, ZELBORAF 240 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLETPizotifen
go.drugbank.com/drugs/DB06153ApprovedSandomigran is available in a number of countries but is not approved by the FDA nor EMA. … [A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AntagonistsProducts: Pizogran Tablet 0.5 mg, SANDOMIGRAN 0,5 MG KAPLI TABLET, 30 ADETTrastuzumab deruxtecan
go.drugbank.com/drugs/DB14962ApprovedInvestigationalTrastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. … [L10842] It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of its class.
Categories: MATE 2 Substrates, P-glycoprotein substratesSynonyms: T-DXd, T- DXdPhenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalPhenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. … Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization.
Mixtures: DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ, COOLING 5 PLUSCategories: Compounds used in a research, industrial, or household settingLynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of [norethisterone].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRİL 5 MG TABLET, 30 ADETEucalyptus gum
go.drugbank.com/drugs/DB15537ApprovedInvestigationalProducts: Soulage LA Toux - Cap 230mgRisdiplam
go.drugbank.com/drugs/DB15305ApprovedInvestigational[L15331,L15336] Set to be substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a novel and relatively accessible treatment option for patients with SMA regardless … Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA).
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: Evrysdi Powder for oral solution 0.75 mg/mL, EVRYSDI POWDER FOR ORAL SOLUTION 0.75 MG/MLHydroxyproline
go.drugbank.com/drugs/DB08847ApprovedTherapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds. … Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products.
Mixtures: Gongjinhyang Mi Luxury Foundation 1, The History Of Whoo Gongjinhyang Mi Pact 1Synonyms: trans-4-Hydroxy-L-proline, trans-L-HydroxyprolinePropiverine
go.drugbank.com/drugs/DB12278ApprovedPropiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) [A32576]. … OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents [L2327], [L2328].
Categories: Adrenergic alpha-1 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: MİCTONORM 5 MG KAPLI TABLET, 98 ADET, MİCTONORM 15 MG KAPLI TABLET, 56 ADET