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Desmoteplase
go.drugbank.com/drugs/DB04925InvestigationalWhen a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. … Desmoteplase is a chemical in the saliva of vampire bats. It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots.
Teglarinad chloride
go.drugbank.com/drugs/DB05217InvestigationalIn vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. … Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis.
EC-0652
go.drugbank.com/drugs/DB15340ExperimentalEC-0652 is under investigation in clinical trial NCT02202447 (Phase 1 of EC1169 In Patients With Recurrent MCRPC).
MUC1 Dendritic Cell Vaccine
go.drugbank.com/drugs/DB05477InvestigationalThese cells are then given back to a patient as a vaccine in order to allow for a potent immune response to cancer. … The Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign antigens to the T-cells to initiate a primary response in the effector arm of the immune system
Etiprednol dicloacetate
go.drugbank.com/drugs/DB05442InvestigationalAnti-asthmatic effects were associated with decreased cytokine production in lipopolysaccharide-stimulated lymphocytes and attenuated lectin-induced proliferation of blood mononuclear cells in tissue culture … Etiprednol dicloacetate (BNP-166) is a soft corticosteroid with anti-inflammatory properties that has been indicated in the treatment of asthma and Chron's disease.
D-Serine
go.drugbank.com/drugs/DB03929ApprovedInvestigationalWithdrawnA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
αAβ–Gas6
go.drugbank.com/drugs/DB17069ExperimentalαAβ–Gas6 is a chimeric fusion protein being investigated in preclinical studies as an immunotherapeutic agent for Alzheimer's disease (AD). … for receptor kinases expressed in glial cells.
Maritime pine extract
go.drugbank.com/drugs/DB15786InvestigationalCategories: Compounds used in a research, industrial, or household settingVitis vinifera seed
go.drugbank.com/drugs/DB16606InvestigationalCategories: Compounds used in a research, industrial, or household settingHomidium
go.drugbank.com/drugs/DB17031InvestigationalHomidium is a group II compound with trypanocidal effects.
Categories: Compounds used in a research, industrial, or household setting