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Pralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals. … Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme.
Synonyms: 2-PAMCategories: Compounds used in a research, industrial, or household settingPolyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Mixtures: SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML, Murine Tears 1Categories: Compounds used in a research, industrial, or household settingSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigationalIt is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. … in December 2022 for the treatment of flares in adult patients with generalized pustular psoriasis.
Synonyms: Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain), disulfide with humanized monoclonal BI 655130 kappa-chain, dimerProducts: Spevigo 450 mg/7,5 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 2 ADETValerian
go.drugbank.com/drugs/DB13196ApprovedValerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance. … Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood.
Mixtures: VALERIANA E LUPPOLO DISPERT, VALERIANA E LUPPOLO DISPERTCategories: Cytochrome P-450 CYP2C19 Inducers, Cytochrome P-450 CYP3A InducersBrivaracetam
go.drugbank.com/drugs/DB05541ApprovedInvestigationalBrivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184]. … It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 [L760].
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: BRIVIACT®10 MG, BRIVIACT® 10 MG/ML SOLUCIÓN ORALCreatinine Clearance 5-15 mL/min
go.drugbank.com/conditions/DBCOND0133572Drugs: Amino acidsSynonyms: Creatinine Clearance 5-15 mL/minXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalIt is widely used as a sugar substitute and in "sugar-free" food products. … The recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081].
Mixtures: Fluor-a-day, Fluor-a-dayCategories: Compounds used in a research, industrial, or household settingEthosuximide
go.drugbank.com/drugs/DB00593ApprovedInvestigationalAn anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSynonyms: 2-ethyl-2-methylsuccinimide, (±)-2-ethyl-2-methylsuccinimideIntracellular exo-alpha-(1->5)-L-arabinofuranosidase
go.drugbank.com/bio_entities/BE0001766TargetGeobacillus stearothermophilusCatalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans).
Polypeptides: Intracellular exo-alpha-(1->5)-L-arabinofuranosidaseSynonyms: Intracellular arabinan exo-alpha-(1->5)-L-arabinosidaseInterferon beta-1b
go.drugbank.com/drugs/DB00068ApprovedInvestigationalHuman interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Synonyms: Interferon beta-1b, Interferon-beta-1bCategories: Interferon Type I, Cytochrome P-450 CYP1A2 Inhibitors