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Displaying results 5001 - 5010 of 10000 in total
  1. Drug

    Tromantadine

    go.drugbank.com/drugs/DB13288
    Approved

    Tromantadine is marketed as Viru-Merz in the Czech Republic [L5740]. It is an antiviral used in the treatment of herpes zoster and simplex.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  2. Drug

    Glisoxepide

    go.drugbank.com/drugs/DB01289
    Investigational

    However it inhibits taurocholate uptake only in the absence of sodium ions. … These results are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid cholate. [A31819,A31820]

    Categories: Drugs Used in Diabetes
  3. Drug

    Benzquinamide

    go.drugbank.com/drugs/DB00767
    ApprovedWithdrawn

    The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors. … Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.

  4. Drug

    PSN9301

    go.drugbank.com/drugs/DB05001
    Experimental

    PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. … PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for meal-related dosing.

  5. Drug

    Lexatumumab

    go.drugbank.com/drugs/DB06599
    Investigational

    Lexatumumab is a fully humanized, high-affinity immunoglobulin G(1 lambda) monoclonal antibody (mAb).

  6. Drug

    Selisistat

    go.drugbank.com/drugs/DB13978
    Investigational

    Enhances p53 acetylation in response to DNA damaging agents. … Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3

  7. Drug

    Drostanolone propionate

    go.drugbank.com/drugs/DB14655
    ApprovedIllicit

  8. Drug

    Penicillium glaucum

    go.drugbank.com/drugs/DB14171
    Approved

    Penicillium glaucum allergenic extract is used in allergenic testing.

    Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Fungal Allergenic Extract
  9. Drug

    QR-334

    go.drugbank.com/drugs/DB05473
    Experimental

    QR-334 is under investigation for the treatment of sialorrhea. Sialorrhea is an excess secretion of saliva produced by the salivary glands, resulting in drooling. … No pharmaceutical interventions currently exist to treat sialorrhea.

  10. Drug

    MK-212

    go.drugbank.com/drugs/DB12111
    Investigational

    MK-212 has been used in trials studying the treatment of Alcoholism.

    Salts: MK-212 hydrochlorideCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome