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Displaying results 5001 - 5010 of 10000 in total
  1. Target

    5-hydroxytryptamine 2 receptor

    go.drugbank.com/bio_entities/BE0004881
    TargetHumans

    Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773).

    Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2A
  2. Target

    5-hydroxytryptamine receptor 2

    go.drugbank.com/bio_entities/BE0004957
    TargetHumans

    Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773).

    Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2A
  3. Drug

    Dipyridamole

    go.drugbank.com/drugs/DB00975
    ApprovedInvestigational

    A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.

    Mixtures: AGGRENOX ® CAPSULAS DE LIBERACION RETARDADA, Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mgCategories: Phosphodiesterase 5 Inhibitors, P-glycoprotein inhibitors
  4. Drug

    3-isobutyl-1-methyl-7H-xanthine

    go.drugbank.com/drugs/DB07954
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione, 1-methyl-3-isobutylxanthine
  5. Drug

    AD-214

    go.drugbank.com/drugs/DB18412
    Investigational

    Synonyms: Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and 3 of the Fc region of a mutated human IgG1
  6. Drug

    Cefadroxil

    go.drugbank.com/drugs/DB01140
    ApprovedInvestigationalVet approvedWithdrawn

    Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: D-Cefadroxil
  7. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).

    Mixtures: DESCASE 5 MG / 10 MG FILM KAPLI TABLET ,90 ADET, DESCASE 5 MG / 10 MG FILM KAPLI TABLET ,30 ADETCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-Ring
  8. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.

    Mixtures: METGLITAL LEX 850 MG / 2 MG TABLETAS DE LIBERACION PROLONGADA, METGLITAL LEX 850 MG / 2 MG TABLETAS DE LIBERACION PROLONGADACategories: MATE 2 Substrates, MATE 1 Substrates
  9. Drug

    Cefpodoxime

    go.drugbank.com/drugs/DB01416
    ApprovedInvestigationalVet approved

    Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.

    Mixtures: INFEX PLUS 50/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, INFEX PLUS 100/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Latrunculin A

    go.drugbank.com/drugs/DB02621
    Investigational

    Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer.

    Synonyms: (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one, LAT-A