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POU domain, class 5, transcription factor 1
go.drugbank.com/bio_entities/BE0003665TransporterTargetHumansTranscription factor that binds to the octamer motif (5'-ATTTGCAT-3').
Polypeptides: POU domain, class 5, transcription factor 12,3-diketo-5-methylthiopentyl-1-phosphate enolase
go.drugbank.com/bio_entities/BE0003741TargetGeobacillus kaustophilus (strain HTA426)Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
Polypeptides: 2,3-diketo-5-methylthiopentyl-1-phosphate enolaseSynonyms: DK-MTP-1-P enolasePhenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalPhenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. … Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization.
Mixtures: DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ, COOLING 5 PLUSCategories: Compounds used in a research, industrial, or household settingSodium phosphate, monobasic
go.drugbank.com/drugs/DB09449ApprovedInvestigationalSodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Mixtures: AMINOPLASMAL-5% E INFUSION, E-Z CupsProducts: BT ORAL SOLUSYON 45 ML, BT ORAL SOLUSYON 90 MLEfmarodocokin alfa
go.drugbank.com/drugs/DB16398InvestigationalEfmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Synonyms: HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10>P(158)), CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS,, INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN FC REGION (81-GLYCINE)), DIMERHypromellose
go.drugbank.com/drugs/DB11075ApprovedInvestigationalIt is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong … It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations [A24840].
Synonyms: Cellulose, 2-hydroxypropyl methyl etherSalts: Hypromellose 2910 (15 mPa.S), Hypromellose 2910 (3 mPa.S)Tigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalTigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. … Food and Drug Administration (FDA) on June 17, 2005.
Synonyms: (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamideProducts: MRSACIN 50 MG I.V. INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON,FLAKON, 1 ADET, TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEAmifostine
go.drugbank.com/drugs/DB01143ApprovedInvestigationalA phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Categories: Compounds used in a research, industrial, or household settingProducts: ETHYOL 500 MG IV INFUZYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADETBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalBenralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction.
Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsProducts: FASENRA®, Fasenra 30 mg solution for injection in pre-filled syringeDeoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalDeoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that … It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical
Mixtures: Debiline H, Duchol EctSynonyms: (3α,5β,12α)-3,12-dihydroxycholan-24-oic acid