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Fondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalThe monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant factor, antithrombin III (ATIII). … Fondaparinux may be used: to prevent venous thromboembolism in patients who have undergone orthopedic surgery of the lower limbs (e.g. hip fracture, hip replacement and knee surgery); to prevent VTE in
Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigational[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor [dabigatran].
Prasterone
go.drugbank.com/drugs/DB01708ApprovedInvestigationalNutraceuticalPrasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. … DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter dietary supplements.
Categories: Sex Hormones and Modulators of the Genital SystemPolyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826].
Mixtures: FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ, NOVAQUA %1,4 + %0,6 TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ, 30 ADETMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease and hemophilia A. It was first approved by the FDA in 2015. … [L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid the theoretical risk of pathogen transmission from plasma donors.[A32262]
Mixtures: ENJEKSİYON/İNFÜZYON İÇİN TOZ VE ÇÖZÜCÜ, ENJEKSİYON/İNFÜZYON İÇİN TOZ VE ÇÖZÜCÜErgoloid mesylate
go.drugbank.com/drugs/DB01049Approved[T90] The derivatives of this fungus are identified to be about 350 different substances from which the components of the ergoloid mesylate mixture are composed of the dihydrogenated ergot alkaloid derivatives … [L2640] To know more about the individual components of the ergoloid mixture, please visit [DB11275], [DB11274], [DB11273] and [DB13345].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeHydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalStructurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. … Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeFlavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigational[A274616,L54226] FMN is composed of an isoalloxazine ring - which serves as the active redox center - attached to a ribityl phosphate chain. … Flavin mononucleotide (FMN), also known as riboflavin 5'-phosphate, is one of the two major coenzymes derived from [riboflavin] (vitamin B2) and is one of the principal forms in which dietary riboflavin
Mixtures: Multivit Et Fer Ampoules Et Comprimes, Dynam Ampoule Et TabletTiratricol
go.drugbank.com/drugs/DB03604ApprovedInvestigationalby chronic tissue thyrotoxicosis and abnormal neuronal development due to the impaired thyroid hormone uptake in the brain. … Tiratricol is an analogue and active metabolite of the thyroid hormone triiodothyronine (T3).
Categories: Agents used to treat hypothyroidism