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Aceclofenac
go.drugbank.com/drugs/DB06736ApprovedAceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher ant...
Mixtures: ZERODOL PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesThonzylamine
go.drugbank.com/drugs/DB11235ApprovedThonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Mixtures: Nasopen PE, Poly Hist PDHomosalate
go.drugbank.com/drugs/DB11064ApprovedHomosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by...
Mixtures: Olay Luminous Whip Active Moisturizer Broad Spectrum SPF 30 Sales Samples, Olay Total Effects Whip Active Moisturizer Broad Spectrum SPF 30 Sunscreen Sales SamplesCalcium lactate
go.drugbank.com/drugs/DB13231ApprovedVet approvedCalcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct f...
Categories: Calcium SaltsYSIL6
go.drugbank.com/drugs/DB05017ExperimentalThe molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell proliferation and migration.
Obiltoxaximab
go.drugbank.com/drugs/DB05336ApprovedObiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.
AZD2389
go.drugbank.com/drugs/DB22104Investigational[L54978] It is currently undergoing safety, tolerability, and PK/PD profiling in clinical trials (e.g.
Abrocitinib
go.drugbank.com/drugs/DB14973ApprovedInvestigationalAbrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal trans...
Synonyms: PF-04965842Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigationalBaricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthrit...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates