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NV1020

NV1020, a genetically engineered herpes simplex virus, is a novel anticancer therapeutic.

Human umbilical cord blood mononuclear cell-conditioned medium

Thus, the media in which they are cultured is believed to also have therapeutic potential. … Then, the medium is filtered and separated from the HUCBCs.

Lemzoparlimab

Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or … IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).

Biapenem

It is a carbapenem antibiotic with a methyl group on the 1-beta position, which gives it stability against degradation by dehydropeptidase I.[A275008] … Biapenem has been used in trials studying the treatment of various bacterial infections.

DNB-001

DNB-001 is a first-in-class oral therapy with dual mechanism of action, which is initially being developed for the treatment of glaucoma. … In preclinical animal models, DNB-001 has demonstrated potent IOP- lowering effects as well as neuroprotective effects on the optic nerve.

TST10088

TST10088 is a recombinant variant of a plant toxin belonging to the family of class II ribosome inactivating proteins. … TST10088 has been designed and engineered by Twinstrand to contain a peptide switch that is specifically cleaved by the matrix metalloproteinases which are known to be involved in tumor growth and metastasis

Tengonermin

Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug. … [A233265] It is a recombinant protein and peptide-targeted agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide.

Muparfostat

Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic

Darapladib

Prenalterol