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Displaying results 5151 - 5160 of 10000 in total
  1. Drug

    Propofol

    go.drugbank.com/drugs/DB00818
    ApprovedInvestigationalVet approved

    IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. … Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia.

    Mixtures: Anesthesia S/I-60, Anesthesia S/I-40Categories: P-glycoprotein inducers, Cytochrome P-450 Substrates
  2. Drug

    Polydatin

    go.drugbank.com/drugs/DB11263
    Approved

    Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. … It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229].

    Synonyms: 3,4',5-trihydroxystilbene-3-β-d-glucoside, resveratrol-3-O-b-mono-D-glucoside
  3. Drug

    Ditazole

    go.drugbank.com/drugs/DB08994
    ApprovedWithdrawn

    Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas. … Ditazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanol
  4. Drug

    Berberine

    go.drugbank.com/drugs/DB04115
    ApprovedInvestigationalWithdrawn

    An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. … It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.

    Categories: MATE 1 Substrates, P-glycoprotein substrates
  5. Drug

    Annamycin

    go.drugbank.com/drugs/DB06420
    Investigational

    Synonyms: 2'-Iodo-3'-hydroxy-4'-epi-4-demethoxydoxorubicinCategories: P-glycoprotein inhibitors
  6. Drug

    Romlusevimab

    go.drugbank.com/drugs/DB16494
    Investigational

    Romlusevimab (BRII-198) was under investigation in clinical trials (NCT04479644 and NCT04691180) to treat COVID-19, focusing on its safety, tolerability, and pharmacokinetics.

    Synonyms: IMMUNOGLOBULIN G1-LAMBDA2, ANTI-(SEVERE ACUTE RESPIRATORYSYNDROME CORONAVIRUS 2 (SARS-COV-2) SPIKE (S) GLYCOPROTEIN,RECEPTOR BINDING DOMAIN (RBD)), HOMO SAPIENS MONOCLONALANTIBODY
  7. Drug

    SB-249553

    go.drugbank.com/drugs/DB05285
    Experimental

    SB-249553 is a vaccine that has MAGE-3 cancer antigen and the Adjuvant SBAS-2. It is also under by GlaxoSmithKline to treat melanoma and lung cancer.

  8. Drug

    CHF5633

    go.drugbank.com/drugs/DB18696
    Investigational

    synthetic SP-B analogue. … CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a

    Synonyms: Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue
  9. Drug

    Nafcillin

    go.drugbank.com/drugs/DB00607
    ApprovedInvestigational

    A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersSynonyms: (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)penicillanic acid
  10. Drug

    Thyroglobulin

    go.drugbank.com/drugs/DB01584
    ApprovedWithdrawn

    The active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase. … Thyroglobulin is used to treat hypothyroidism.