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Displaying results 5161 - 5170 of 10000 in total
  1. Drug

    WL-1002

    go.drugbank.com/drugs/DB05346
    Experimental

    WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin (also known as civamide), for the treatment of pain due to osteoarthritis.

  2. Drug

    Propentofylline

    go.drugbank.com/drugs/DB06479
    Experimental

    Categories: Psychostimulants, Agents Used for ADHD and Nootropics, Compounds used in a research, industrial, or household setting
  3. Drug

    Gantenerumab

    go.drugbank.com/drugs/DB12034
    Investigational

    [A244705, A244710, A244745] Gantenerumab is a fully human IgG1κ monoclonal antibody derived from the MorphoSys HuCAL®-Fab1 phage display library and subsequently optimized by _in vitro_ CDR cassette … Alzheimer's disease (AD) is the most common cause of dementia in elderly patients, with classical histopathological hallmarks including extracellular amyloid-beta (Aβ) plaques and intraneuronal neurofibrillary

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    Vilazodone

    go.drugbank.com/drugs/DB06684
    ApprovedInvestigational

    Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. … Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].

    Categories: Serotonin antagonist and reuptake inhibitors (SARIs)
  5. Drug

    Oglufanide

    go.drugbank.com/drugs/DB05779
    Investigational

    being acquired by Implicit Bioscience in 2005. … Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before

    Categories: Amino Acids, Peptides, and Proteins, Compounds used in a research, industrial, or household setting
  6. Drug

    Choriogonadotropin alfa

    go.drugbank.com/drugs/DB00097
    ApprovedInvestigational

    Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN … -13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit).

    Categories: Gonadotropins and Antigonadotropins, Genito Urinary System and Sex Hormones
  7. Indication

    Previously treated with an HCV regimen containing an NS5A inhibitor Chronic Hepatitis C Genotype 1

    go.drugbank.com/conditions/DBCOND0093786
    Drugs: Voxilaprevir
    Synonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic Hepatitis C Genotype 1
  8. Drug

    Sofalcone

    go.drugbank.com/drugs/DB05197
    Experimental

    Sofalcone is a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori. on adherence, production of vacuolating toxin (VT), and induction of interleukin-8 (IL-8) secretion … by H. pylori.

  9. Drug

    Cyclopentamine

    go.drugbank.com/drugs/DB08999
    ApprovedWithdrawn

    Cyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. … It has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.

  10. Drug

    Calcitonin gene-related peptide

    go.drugbank.com/drugs/DB06379
    Investigational

    As a potential drug, it has demonstrated in preclinical studies a profile that could make it an ideal anti-asthmatic drug candidate with bronchodilatory, bronchoprotecting and anti-inflammatory properties … The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.

    Categories: Amino Acids, Peptides, and Proteins