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Folic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedFolic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … When used in high doses such as for cancer therapy, or in low doses such as for Rheumatoid Arthritis or psoriasis, [DB00563] impedes the body's ability to create folic acid.
Synonyms: N-pteroyl-L-glutamic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acidMixtures: Stress B Complex With C and E Tab, Stress B Complex With C, E & IronLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.
Synonyms: 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazoleMixtures: COZAAR COMP 50MG/12.5MG, LOSAR-Q COMP 100/25MG FTAAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigational[A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335] … It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine.
Products: AZACITIDINA EGDocusate
go.drugbank.com/drugs/DB11089ApprovedInvestigationalHowever the effectiveness of docusate in treating constipation remains unclear, as several studies report docusate to be no more effective than placebo for increasing the frequency of stool or stool softening … Still docusate is available in over-the-counter products as a common laxative.
Mixtures: E-Vac Plus, EX-lax Gentle StrengthProducts: H E B Stool Softener laxative, EX-lax Stool Softener - Tab 100 mgPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalIt is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration.
Mixtures: PERINDOPRIL E AMLODIPINA EG, PERINDOPRIL E AMLODIPINA EGCategories: Agents Acting on the Renin-Angiotensin SystemTuberous Sclerosis Complex with Subependymal Giant Cell Astrocytoma
go.drugbank.com/conditions/DBCOND0025535Drugs: EverolimusSynonyms: Tuberous Sclerosis Complex with Subependymal Giant Cell AstrocytomaProtein S100-A12
go.drugbank.com/bio_entities/BE0001206TargetHumansS100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.
Synonyms: EN-RAGEPixantrone
go.drugbank.com/drugs/DB06193ApprovedWithdrawnAnother phase III trial, PIX-R, is now ongoing to clarify pixantrones place in therapy. It will compare pixantrone efficacy to that of gemcitabine. [2] … Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL.
Bicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalBicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers.
Products: BICALUTAMIDE EG, BICALUTAMIDE EG STADATobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigational[A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics … [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to
Mixtures: TOBRAMICINA E DESAMETASONE EG, TOBRAMICINA E DESAMETASONE DOC GENERICIProducts: TOBRAMICINA EG, Tobramycin in Sodium Chloride