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PX-12
go.drugbank.com/drugs/DB05448InvestigationalPX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits … Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Methylpropyl-2-imidazolyl disulfideRurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigational[L40119] Rurioctocog alfa pegol is a covalent conjugate of [octocog alfa], which is a recombinant factor VIII produced by recombinant DNA technology from a Chinese hamster ovary cell line. … Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor.
Tretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticalTretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). … [A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L.
Synonyms: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL)International brands: Stieva-AMethscopolamine
go.drugbank.com/drugs/DB11315ApprovedMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. … Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products.
Mixtures: Re Drylex, AlleRx-DOctisalate
go.drugbank.com/drugs/DB11062ApprovedOctyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. … Octyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm. It is an ester of salicylic acid and 2-ethylhexanol.
Mixtures: OBAGI-C RX SYSTEM C-EXFOLIATING DAY with Vitamin C, Obagi-C C-Rx System Normal-Dry Skin InterventionCategories: Compounds used in a research, industrial, or household settingDexchlorpheniramine maleate
go.drugbank.com/drugs/DB09555ApprovedDexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture. … Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine.
Mixtures: Re Drylex, SP-SINUDYL SYRUPCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsAvobenzone
go.drugbank.com/drugs/DB09495ApprovedInvestigationalAvobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. … Sunscreens containing avobenzone is indicated for providing protection from the sun.
Mixtures: SPF Rx - SPF 30 Mango Lip Balm, SPF Rx - Sport Sunscreen SPF 30Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnIt is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol.
Mixtures: Body Rox, KORDEL`S EXECUTIVE B TABLETCategories: Vitamin B ComplexOmega-3-acid ethyl esters
go.drugbank.com/drugs/DB09539ApprovedInvestigationalOmega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand name Lovaza[FDA Label][L5849]. … Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower
Synonyms: omega-3 acid ethyl esters, Omega-3-acid ethyl estersMixtures: Omega-3 Rx Complete, Mi-Omega NFSodium fluorophosphate
go.drugbank.com/drugs/DB09484ApprovedInvestigationalSodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Mixtures: Colgate Total Zx Pro-Shield Plus Sensitive, Ron 2Categories: Compounds used in a research, industrial, or household setting