Search
Maraviroc
go.drugbank.com/drugs/DB04835ApprovedInvestigationalMaraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the … It was originally labelled as UK-427857 during development but was assigned the Maraviroc name as it entered trials. It was approved for use by the FDA in August, 2007.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: CELSENTRI® 150 MG, CELSENTRI® 300 MGPyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Synonyms: 2-carbamylpyrazine, 2-pyrazinecarboxamideMixtures: RIFAMPICIN 75 MG/ISONIAZID 50 MG/PYRAZINAMIDE 150 MG, RINCURE ® 3 FDC TABLETAS CON PELICULACholine
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalIt is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.
Synonyms: N,N,N-trimethylethanol-ammonium, N-trimethylethanolamineMixtures: Stress B With 1000 Mg Vitamin C, Pour Ma SantéPrazepam
go.drugbank.com/drugs/DB01588ApprovedIllicitPrazepam is a benzodiazepine that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: PRAZEPAM EGModafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalModafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. … Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesSynonyms: 2-((diphenylmethyl)sulfinyl)acetamideCytosolic purine 5'-nucleotidase
go.drugbank.com/bio_entities/BE0000261TargetEnzymeHumansBroad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705).
Polypeptides: Cytosolic purine 5'-nucleotidaseSynonyms: High Km 5'-nucleotidase, Cytosolic 5'-nucleotidase II5'(3')-deoxyribonucleotidase, mitochondrial
go.drugbank.com/bio_entities/BE0001515TargetHumansDephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879).
Polypeptides: 5'(3')-deoxyribonucleotidase, mitochondrialSynonyms: Deoxy-5'-nucleotidase 2, 5',3'-nucleotidase, mitochondrial5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
go.drugbank.com/bio_entities/BE0001620TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
Polypeptides: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseFunction: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activityOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001677TargetEnzymeEscherichia coli (strain K12)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001956TargetBacillus subtilis (strain 168)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseFunction: orotidine-5'-phosphate decarboxylase activity