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Displaying results 5201 - 5210 of 10000 in total
  1. Drug

    Elacytarabine

    go.drugbank.com/drugs/DB05494
    Investigational

    melanoma and ovarian cancer. … Elacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  2. Drug

    Methyl undecenoyl leucinate

    go.drugbank.com/drugs/DB11272
    Approved

    It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes. … Methyl undecenoyl leucinate is an active ingredient in whitening creams.

  3. Drug

    Evofosfamide

    go.drugbank.com/drugs/DB06091
    Investigational

    TH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide. … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated.

  4. Drug

    Sofpironium

    go.drugbank.com/drugs/DB19325
    Approved

    [A264153] Sofpironium is rapidly converted to a less active metabolite, BBI-4010, after exerting its activity, thereby limiting the incidence and/or severity of systemic anticholinergic effects. … [L51108,L51109] Sofpironium bromide (Sofdra) was approved by the FDA in June 2024 for the topical treatment of primary axillary hyperhidrosis.

  5. Drug

    Eprazinone

    go.drugbank.com/drugs/DB08990
    ApprovedWithdrawn

    Eprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.

    Categories: Cough and Cold Preparations
  6. Drug

    Dental Mesenchymal Pulp Stem Cells

    go.drugbank.com/drugs/DB15737
    Investigational

    DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 or CD45. … They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is non-invasive, easily accessible, and allows for an alternate use of teeth that are usually

  7. Drug

    Nepafenac

    go.drugbank.com/drugs/DB06802
    ApprovedInvestigational

    It is used to treat pain and inflammation associated with cataract surgery.

  8. Drug

    Tolcapone

    go.drugbank.com/drugs/DB00323
    ApprovedInvestigationalWithdrawn

    It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound.

  9. Drug

    Neisseria meningitidis group Y capsular polysaccharide tetanus toxoid conjugate antigen

    go.drugbank.com/drugs/DB15682
    ApprovedInvestigational

  10. Drug

    BMS-986263

    go.drugbank.com/drugs/DB28821
    Investigational

    BMS-986263 is under investigation in clinical trial NCT04267393 (Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)).

    Synonyms: ND-L02-s0201