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Displaying results 5201 - 5210 of 10000 in total
  1. Target

    Metabotropic glutamate receptor 5

    go.drugbank.com/bio_entities/BE0001192
    TargetHumans

    G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a...

    Polypeptides: Metabotropic glutamate receptor 5
  2. Target

    5-hydroxytryptamine receptor 5A

    go.drugbank.com/bio_entities/BE0004688
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521).

    Polypeptides: 5-hydroxytryptamine receptor 5ASynonyms: 5-HT-5, 5-HT5A
  3. Target

    5-hydroxytryptamine 2 receptor

    go.drugbank.com/bio_entities/BE0004881
    TargetHumans

    Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed

    Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2A
  4. Target

    5-hydroxytryptamine receptor 2C

    go.drugbank.com/bio_entities/BE0004882
    TargetRat

    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). … Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)

    Polypeptides: 5-hydroxytryptamine receptor 2CSynonyms: 5-HT1C, 5-HT-1C
  5. Target

    5-hydroxytryptamine receptor 2

    go.drugbank.com/bio_entities/BE0004957
    TargetHumans

    Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed

    Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2A
  6. Target

    Chromobox protein homolog 5

    go.drugbank.com/bio_entities/BE0009056
    TargetHumans

    Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression (PubMed:40440427). In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phospho...

    Polypeptides: Chromobox protein homolog 5Synonyms: Heterochromatin protein 1 homolog alpha
  7. Target

    Serine repeat antigen 5

    go.drugbank.com/bio_entities/BE0009196
    TargetPlasmodium falciparum

    Polypeptides: Serine repeat antigen 5
  8. Target

    5-hydroxytryptamine receptor 3D

    go.drugbank.com/bio_entities/BE0009585
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: 5-HT3D, 5-HT3-D
  9. Drug

    Iron Dextran

    go.drugbank.com/drugs/DB00893
    ApprovedInvestigationalVet approved

    Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. … Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.

    Mixtures: Irospan 24/6Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Eltrombopag

    go.drugbank.com/drugs/DB06210
    ApprovedInvestigational

    ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood. … Eltrombopag has also been recently approved (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: REVOLADE ® TABLETAS 50 MG, REVOLADE® TABLETAS 25 MG