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3-oxo-5-alpha-steroid 4-dehydrogenase 2
go.drugbank.com/bio_entities/BE0000585TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Converts testosterone into 5-alpha-dihydrotestosterone (DHT), the most active androgen in the prostate, as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2Synonyms: Steroid 5-alpha-reductase 2, S5AR 2Actin-related protein 2/3 complex subunit 5
go.drugbank.com/bio_entities/BE0004255TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in th...
Polypeptides: Actin-related protein 2/3 complex subunit 5Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
go.drugbank.com/bio_entities/BE0009517TargetHumansPreferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration (PubMed:26774281).
Polypeptides: Phosphatidylinositol 5-phosphate 4-kinase type-2 betaSynonyms: PtdIns(5)P-4-kinase isoform 2-beta, 1-phosphatidylinositol 5-phosphate 4-kinase 2-betaPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma
go.drugbank.com/bio_entities/BE0009518TargetHumansPhosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.
Polypeptides: Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaSynonyms: PI(5)P 4-kinase type II gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gammaPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalPeramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. … The injectable intravenous formulation of peramivir was approved by the FDA in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and older who have been symptomatic
Products: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (5 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (3 Adet)Insulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalDue to its duration of action of around 5 hours, Humalog is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the … Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml, HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/mlCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersGemifloxacin
go.drugbank.com/drugs/DB01155ApprovedInvestigationalGemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.
Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesProducts: ONFACT 320 MG FİLM TABLET, 5 ADET, FACTIVE 320 MG FİLM TABLET, 5 ADETGoserelin
go.drugbank.com/drugs/DB00014ApprovedInvestigationalGoserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. … In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state.
Products: ZOLADEX ® LA 10.8 MG, ZOLADEX ® 3.6MGGalcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigationalA pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060] … Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP).
Products: EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET, EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADETSebelipase alfa
go.drugbank.com/drugs/DB11563ApprovedInvestigational[L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. … In addition, patients with LAL deficiency typically develop dyslipidemia, which itself contributes to a number of adverse cardiovascular outcomes.
Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.