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Displaying results 5271 - 5280 of 10000 in total
  1. Drug

    MVC-COV1901

    go.drugbank.com/drugs/DB15854
    Investigational

    MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. … As of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity (NCT04487210).

  2. Drug

    Licofelone

    go.drugbank.com/drugs/DB04725
    Experimental

    Developed by the German pharmaceutical company, Merckle GmbH, together with EuroAlliance partners Alfa Wassermann and Lacer, licofelone (ML3000) is a dual COX/LOX inhibitor and the first member of this … new class of analgesic and anti-inflammatory drugs.

  3. Drug

    Levorphanol

    go.drugbank.com/drugs/DB00854
    Approved

    It is nearly as effective orally as by injection.

  4. Drug

    Imidacloprid

    go.drugbank.com/drugs/DB11421
    ExperimentalVet approved

    , Prothor, and Winner. … Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise

    Mixtures: Advocate Spot-on Solution for Small Cats and Ferrets
  5. Drug

    Dichlorvos

    go.drugbank.com/drugs/DB11397
    ExperimentalVet approved

    from insect infestations. … Dichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity, and cancer.

  6. Drug

    Mirfentanil

    go.drugbank.com/drugs/DB09175
    Experimental

    to discriminate morphine from naloxone. … At high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.

  7. Drug

    Spermidine

    go.drugbank.com/drugs/DB03566
    Investigational

    Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

  8. Drug

    Cosibelimab

    go.drugbank.com/drugs/DB15770
    ApprovedInvestigational

    On December 13, 2024, cosibelimab was approved by the FDA for the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma [L52690] as the first approved anti-PD-L1 therapy in the

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: anti-Pd-l1 monoclonal antibody CK-301, IMMUNOGLOBULIN G1, ANTI-(HUMAN PROGRAMMED DEATH-LIGAND 1) (HUMAN MONOCLONAL CK-301 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CK-301 .LAMBDA.-CHAIN, DIMER
  9. Drug

    Proscillaridin

    go.drugbank.com/drugs/DB13307
    Experimental

    Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). … ] and triggering cell death and blocking cell proliferation of glioblastoma cell lines [A27194].

  10. Drug

    Vilazodone

    go.drugbank.com/drugs/DB06684
    ApprovedInvestigational

    Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. … Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].

    Categories: Serotonin antagonist and reuptake inhibitors (SARIs)