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Displaying results 521 - 530 of 10000 in total
  1. Target

    Olfactory receptor 1D2

    go.drugbank.com/bio_entities/BE0013079
    TargetHumans

    Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro.

    Polypeptides: Olfactory receptor 1D2Synonyms: Olfactory receptor 17-4, Olfactory receptor OR17-6
  2. Target

    Relaxin receptor 2

    go.drugbank.com/bio_entities/BE0017729
    TargetHumans

    Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. … May also be a receptor for Leydig insulin-like peptide (INSL3)

    Polypeptides: Relaxin receptor 2Synonyms: Leucine-rich repeat-containing G protein-coupled receptor 8, G protein-coupled receptor 106
  3. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1. … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons.

    Synonyms: VEXXON-IGF-1, Human somatomedin CCategories: Recombinant Human Insulin-like Growth Factor-1
  4. Drug

    Voxilaprevir

    go.drugbank.com/drugs/DB12026
    ApprovedInvestigational

    Notably, Vosevi is approved for use in patients with genotypes 1-6 who have been previously treated with an NS5A inhibitor, or patients with genotypes 1a or 3 infection and have previously been treated … Voxilaprevir has been available since July 2017 in a fixed dose combination product with [sofosbuvir] and [velpatasvir] as the commercially available product Vosevi.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A
  6. Drug

    Potassium perchlorate

    go.drugbank.com/drugs/DB09418
    ApprovedWithdrawn

    The therapeutic use of potassium perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and nephrotic syndrome [L2364]. … The use of potassium perchlorate as a component in sealing gaskets for food containers has been revoked by the FDA following the use being abandoned by the industry [L2365].

  7. Drug

    Lincomycin

    go.drugbank.com/drugs/DB01627
    ApprovedInvestigationalVet approved

    [A190621] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains … Lincomycin is a lincosamide antibiotic first isolated from the soil bacterium _Streptomyces lincolnensis_ in Lincoln, Nebraska.

    Categories: Heterocyclic Compounds, 1-RingProducts: LINCOCIN 2 ML 600 MG 1 AMPUL, LINKAMIN ENJEKTABL 600 MG/2 ML, 1 ADET
  8. Target

    Dopamine receptor D1

    go.drugbank.com/bio_entities/BE0000020
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … DRD1 can also couple with G(q) by forming a heteromer with the ghrelin receptor GHSR in hippocampal neurons independently of ghrelin (By similarity).

    Polypeptides: Dopamine receptor D1Synonyms: Dopamine D1 receptor, D(1A) dopamine receptor
  9. Target

    Growth hormone receptor

    go.drugbank.com/bio_entities/BE0000075
    TargetHumans

    Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth (PubMed:1549776, PubMed:2825030, PubMed:8943276).

    Polypeptides: Growth hormone receptorSynonyms: GH receptor, Somatotropin receptor
  10. Target

    Dopamine receptor D5

    go.drugbank.com/bio_entities/BE0000145
    TargetHumans

    G protein-coupled receptor for dopamine, a catecholamine neurotransmitter hormone that functions as the brain's 'reward chemical', driving motivation, reinforcement learning and pleasure (PubMed:11500503 … Dopamine receptors can be classified in two categories: (1) DRD5 (together with DRD1) is a D1-type receptor and is coupled to G(s) G proteins, mediating activation of adenylate cyclase activity, while

    Polypeptides: Dopamine receptor D5Synonyms: D(1B) dopamine receptor, Dopamine D5 receptor