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Displaying results 521 - 530 of 10000 in total
  1. Drug

    N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide

    go.drugbank.com/drugs/DB07801
    Experimental

    Synonyms: N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide
  2. Drug

    Pindolol

    go.drugbank.com/drugs/DB00960
    ApprovedInvestigational

    Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]

    Synonyms: 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-olInternational brands: Blockin L, Blocklin L
  3. Drug

    Mavacamten

    go.drugbank.com/drugs/DB14921
    ApprovedInvestigational

    Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione
  4. Drug

    Sertindole

    go.drugbank.com/drugs/DB06144
    ApprovedWithdrawn

    It is a phenylindole derivative used in the treatment of schizophrenia. … Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck.

    Synonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  5. Drug

    Cladribine

    go.drugbank.com/drugs/DB00242
    ApprovedInvestigational

    [A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment multiple sclerosis.[A263718] … Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes.

    Categories: 2-Chloroadenosine, P-glycoprotein substratesSynonyms: (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine
  6. Drug

    4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE

    go.drugbank.com/drugs/DB08159
    Experimental

    Synonyms: 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE
  7. Drug

    2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM

    go.drugbank.com/drugs/DB08615
    Experimental

    Synonyms: 2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM
  8. Drug

    6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE

    go.drugbank.com/drugs/DB07202
    Experimental

    Synonyms: 6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE
  9. Drug

    alpha-D-glucose 6-phosphate

    go.drugbank.com/drugs/DB02007
    Experimental

    Synonyms: 6-O-phosphono-α-D-glucopyranose, alpha-D-glucose 6-phosphate
  10. Drug

    3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE

    go.drugbank.com/drugs/DB08730
    Experimental

    Synonyms: 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE