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Displaying results 521 - 530 of 10000 in total
  1. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. … Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections.

    Synonyms: PE2, 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  2. Drug

    Albuterol

    go.drugbank.com/drugs/DB01001
    ApprovedInvestigationalVet approved

    Salbutamol is formulated as a racemic mixture of the R- and S-isomers. … Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD.

    Mixtures: SALBUTAMOLO E IPRATROPIO BROMURO EG, ULAX-CCategories: Adrenergic beta-2 Receptor Agonists, Cytochrome P-450 CYP3A Inhibitors
  3. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine]. … [A182300] Similar to other opioid medications, tramadol poses a risk for development of tolerance, dependence and abuse.

    Mixtures: TRAMADOLO E PARACETAMOLO EG, TRAMADOLO E PARACETAMOLO EGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Topotecan

    go.drugbank.com/drugs/DB01030
    ApprovedInvestigational

    It works by inhibiting DNA topoisomerases, type I.

    Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexSynonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin
  5. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. … [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion.

    Synonyms: (S)-omeprazole, (S)-(−)-omeprazoleInternational brands: ES-OD
  6. Drug

    Piroxicam cinnamate

    go.drugbank.com/drugs/DB15883
    Investigational

    Categories: Heterocyclic Compounds, 1-RingProducts: SINARTROL INFIAMMAZIONE E DOLORE
  7. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combinati...

    Mixtures: RAMIPRIL COMP PUR 5/25MG, RAMIPRIL COMP PUR 5/25MGCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    Since that time the agent has been a combination component of various prescription and non-prescription over-the-counter cough and cold products and is currently a widely available over-the-counter generic … Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and

    Mixtures: Entex LA, Entex LAInternational brands: Duratuss G
  9. Drug

    Polyaminopropyl biguanide

    go.drugbank.com/drugs/DB15677
    Investigational

    Products: Woosh Antibacterial Pet Wipes, Drop Dream Eye 2
  10. Drug

    Tetryzoline

    go.drugbank.com/drugs/DB06764
    Approved

    [A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant. … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties.

    Synonyms: 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline, 2-Tetralin-1-yl-4,5-dihydro-1H-imidazoleMixtures: ISCHEMOL A, ISCHEMOL A