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PI-0824
go.drugbank.com/drugs/DB05516InvestigationalIt is hoped that use of PI-0824 will reduce or potentially eliminate the need for high dose steroids and drugs that suppress the immune system.
Dental Mesenchymal Pulp Stem Cells
go.drugbank.com/drugs/DB15737InvestigationalThey are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is non-invasive, easily accessible, and allows for an alternate use of teeth that are usually
Human Menstrual Blood-derived Stem Cells
go.drugbank.com/drugs/DB15738InvestigationalBecause this is a non-invasive way to obtain stem cells, it is simple and easy to obtain the stem cells with an absence of ethical issues that may come from obtaining stem cells of the embryonic kind.
Boceprevir
go.drugbank.com/drugs/DB08873ApprovedWithdrawnSubtitutions at amino acid positions 155, 156, or 168 are known to confer resistance.
Products: VICTRELIS ® CAPSULAS 200 MG (MOLECULA PROTEGIDA)Smilagenin
go.drugbank.com/drugs/DB05450InvestigationalPre-clinical work with smilagenin showed it to be neuroprotective against betya-amyloid and glutamate damage which contributes to Alzheimer's disease and reverses the changes in the area of the brain involved
Anti-SARS-CoV-2 REGN-COV2
go.drugbank.com/drugs/DB15691InvestigationalRegeneron's clinical trial will study the effects of this drug on hospitalized COVID-19 patients, symptomatic COVID-19 patients (non-hospitalized), and uninfected individuals at high-risk of infection,
UB-612
go.drugbank.com/drugs/DB16444InvestigationalIt was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658].
COVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalThe rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response. … prime and boost cell responses; they are considered the most powerful antigen-presenting cells, and are able to present antigens through costimulatory signals required for activation of CD4+ and CD8+ T-cells
Fezolinetant
go.drugbank.com/drugs/DB15669ApprovedInvestigational[L46422] It was subsequently approved by the EMA in December 2023 for the same indication.[L50086]
Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalMultiStem is an intravenously-administered, off-the-shelf proprietary product developed which comprises Multipotent Adult Progenitor Cells (MAPCs). Like mesenchymal stem cells, MAPCs are derived from bone-marrow stroma and are non-hemato...