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Displaying results 5311 - 5320 of 10000 in total
  1. Drug

    Sodium sulfide

    go.drugbank.com/drugs/DB11159
    Approved

    Along with its hydrate form, sodium sulfide releases hydrogen sulfide (H2S) when in contact with moist air. … Interestingly, sodium sulfide was shown to have some cardioprotective role against cardiac ischemia or reperfusion injury, as well as protect lungs against ventilator-induced lung injury [A27275].

  2. Drug

    Corynebacterium diphtheriae CRM197 protein

    go.drugbank.com/drugs/DB16712
    ApprovedInvestigational

    Mixtures: Prevenar 13 Suspension For Injection
  3. Drug

    KIN-3248

    go.drugbank.com/drugs/DB17587
    Investigational

    [L45469] In February 2023, Kinnate Biopharma received Fast Track designation from the FDA for KIN-3248 to treat unresectable, locally advanced or metastatic cholangiocarcinoma (CCA).[L45474] … It was designed to mainly target FGFR2 and FGFR3 alterations, which act as oncogenic drivers in 10-20% of cholangiocarcinoma and 20-35% of urothelial cancers, respectively.

  4. Drug

    AVI-4020

    go.drugbank.com/drugs/DB05873
    Investigational

    AVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus disease who have serious neurological impairment (WNV neuroinvasive disease).

  5. Drug

    Cefradine

    go.drugbank.com/drugs/DB01333
    ApprovedWithdrawn

    A semi-synthetic cephalosporin antibiotic.

    Synonyms: (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acidCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  6. Drug

    Flubendazole

    go.drugbank.com/drugs/DB08974
    ApprovedInvestigationalWithdrawn

    Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.

    Products: FLUBENDAZOL HIGEA X 300 MG, FLUBEMIN TABLETAS X 100 MG
  7. Drug

    Adecatumumab

    go.drugbank.com/drugs/DB05006
    Investigational

    EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer. … Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM).

  8. Drug

    Dental Mesenchymal Pulp Stem Cells

    go.drugbank.com/drugs/DB15737
    Investigational

    They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is non-invasive, easily accessible, and allows for an alternate use of teeth that are usually … These cells have innate neurogenic potential as their origins are traced to the embryonic neural crest; there is potential for these cells to create neurons and glial cells.

  9. Drug

    Abivertinib

    go.drugbank.com/drugs/DB15327
    Investigational

    [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. … The study is expected to be completed in March 2021.[L17398]

    Categories: Experimental Unapproved Treatments for COVID-19
  10. Drug

    SVV-001

    go.drugbank.com/drugs/DB06129
    Investigational

    SVV-001 is investigated for use/treatment in cancer/tumors and lung cancer. SVV-001 is a solid. … SVV-001 has also demonstrated cancer-killing specificity 10,000 times higher than that of traditional chemotherapeutics with no overt toxicity at doses one million times higher than effective doses in