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Cefradine is a first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.
- Mechanism
- Curator reviewed
Cefradine is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Cefradine interferes with an autolysin inhibitor.
- Formula / weight
- C16H19N3O4S · 349.405 g/mol (avg)
- First approval
- United States, 1995
- Also known as
- Cephradin · Cephradine
Resolves to
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Which drugs share a target with Cefradine, and which of those have an active Phase 3 trial?