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Chlorotoxin I-131
go.drugbank.com/drugs/DB05462InvestigationalIt is a synthetic version of a neurotoxin isolated from the venom of the Giant Yellow Israeli scorpion Leiurus quinquestriatus.
ZYCOV-D
go.drugbank.com/drugs/DB15892ExperimentalOnce the plasmid DNA is introduced into host cells and the viral protein is translated, it elicits a strong immune response, stimulating the humoral and cellular components of the immune system[L16503]
BBV152
go.drugbank.com/drugs/DB15847InvestigationalAnimal studies in mice, rats, and rabbits reported BBV152 immunogenicity at two separate antigen concentrations with both types of adjuvants.
TRC093
go.drugbank.com/drugs/DB06356InvestigationalTRC093 is a recombinant humanized IgG1k monoclonal antibody.
Doxofylline
go.drugbank.com/drugs/DB09273InvestigationalDoxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects ...
Picolinic acid
go.drugbank.com/drugs/DB05483ExperimentalIt acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan.
Brentuximab
go.drugbank.com/drugs/DB05471InvestigationalIt is available commercially as the monoclonal antibody portion of the antibody-drug conjugate [brentuximab vedotin]. … SGN-30 received orphan drug designation from the FDA in July 2003 for Hodgkin lymphoma and in February 2004 for T-cell lymphomas.
Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalWhile many contain a conserved set of proteins, they also carry unique tissue type-specific proteins.
KIN-3248
go.drugbank.com/drugs/DB17587InvestigationalIt was designed to mainly target FGFR2 and FGFR3 alterations, which act as oncogenic drivers in 10-20% of cholangiocarcinoma and 20-35% of urothelial cancers, respectively.
PI-0824
go.drugbank.com/drugs/DB05516InvestigationalIt is hoped that use of PI-0824 will reduce or potentially eliminate the need for high dose steroids and drugs that suppress the immune system.