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AG0301-COVID19
go.drugbank.com/drugs/DB15856InvestigationalOn September 8, 2020 AnGes announced collaboration with Brickell Biotech, Inc. following completion of Phase 1/2 clinical studies (NCT04463472). … The candidate is a plasmid DNA vaccine developed using an intradermal gene transfer method targeting the SARS-CoV-2 spike protein.
Janssen COVID-19 Vaccine
go.drugbank.com/drugs/DB15857ApprovedInvestigationalThe Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. … SARS-COV-2 challenge.
Synonyms: Ad26.COV2.S, AD26.COV2.S [RECOMBINANT]KBP-COVID-19
go.drugbank.com/drugs/DB15858InvestigationalAs of July 2020, KBP is conducting a Phase 1/2 clinical trial to evaluate the safety and immunogenicity of KBP-COVID-19 vaccine in healthy patients (NCT04473690). … KBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco plants for reproduction.
Inactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences)
go.drugbank.com/drugs/DB15863ExperimentalThe SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells[A219758].
Oral Polio Vaccine
go.drugbank.com/drugs/DB15864InvestigationalThe oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. … The polio vaccine can be either administered in the inactivated form or the oral form, although both series comprises 4 doses and is also interchangeable in administration form so long all as 4 doses are
Pentaglobin
go.drugbank.com/drugs/DB15865Investigational[A220173] It is comprised of [immunoglobulin G (IgG)](https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).[L16353] … Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations.
CK0802
go.drugbank.com/drugs/DB15866Investigational[L16358] On the surface of these T-Reg cells, T-cell lung homing markers are expressed. … CK0802 is an off-the-shelf product composed of allogeneic umbilical cord blood derived regulatory T-cells (T-Reg cells), which can be used intravenously and without HLA matching.
Synonyms: Allogeneic Umbilical Cord Blood Derived Regulatory T-CellsAmniotic Epithelial Cells
go.drugbank.com/drugs/DB15868InvestigationalAmniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus. These cells are potential candidates for allogeneic cell ...
Platelet Lysate
go.drugbank.com/drugs/DB15869InvestigationalBecause white cell antigens are low in prepared lysate, there is a minimized likelihood of immune responses.
Copper oxodotreotide Cu-64
go.drugbank.com/drugs/DB15873Approved[A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron energy lending to improved spatial resolution. … [A220348] In a head-to-head trial, the former tracer detected twice as many lesions as the latter.[A220348]