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Displaying results 5361 - 5370 of 10000 in total
  1. Drug

    RGN6024

    go.drugbank.com/drugs/DB33059
    Experimental

    RGN6024, also known as RGN-6024 or RGNi6024, is a synthetic small-molecule tubulin destabilizer from Reglagene. … RGN6024 remains investigational and is not an approved drug.

  2. Drug

    Prasterone sulfate

    go.drugbank.com/drugs/DB05804
    Investigational

    DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists
  3. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.

  4. Drug

    Nerandomilast

    go.drugbank.com/drugs/DB18237
    ApprovedInvestigational

    [L54141] Nerandomilast exerts both anti-fibrotic and immunomodulatory effects as PDE4 inhibition elevates intracellular cAMP levels and reduces the expression of pro-fibrotic growth factors and inflammatory … It has one chiral center and is the R-stereoisomer.[L54126] On October 7, 2025, nerandomilast was approved as the first new treatment for idiopathic pulmonary fibrosis in more than a decade.

  5. Drug

    Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media

    go.drugbank.com/drugs/DB15728
    Experimental

    The condition medium (CM) derived from these MSCs has also been implicated in therapeutic properties. … In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic.

  6. Drug

    Aclidinium

    go.drugbank.com/drugs/DB08897
    Approved

    Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD).

    Categories: formoterol and aclidinium bromide
  7. Drug

    DFV890

    go.drugbank.com/drugs/DB16461
    Investigational

    knee osteoarthritis), NCT06097663 (coronary heart disease and clonal hematopoiesis of indeterminate potential), NCT05552469 (myeloid diseases), NCT04868968 (familial cold autoinflammatory syndrome), and … DFV890 is under investigation in multiple clinical trials for its efficacy, safety, and tolerability across various conditions: NCT06031844 (coronary heart disease with elevated hsCRP), NCT04886258 (symptomatic

  8. Drug

    Albumin iodinated I-125 serum

    go.drugbank.com/drugs/DB09429
    Approved

    I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.[L12780]

  9. Drug

    Clomethiazole

    go.drugbank.com/drugs/DB06470
    Investigational

    It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. … It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal.

    Categories: Hypnotics and Sedatives
  10. Drug

    Sodium molybdate

    go.drugbank.com/drugs/DB14496
    Approved

    Mixtures: Multiple Vitamins and Minerals, Prenatal Vitamin and Mineral Supplement