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Displaying results 5381 - 5390 of 10000 in total
  1. Drug

    IRX-5183

    go.drugbank.com/drugs/DB05653
    Investigational

  2. Drug

    Anistreplase

    go.drugbank.com/drugs/DB00029
    ApprovedWithdrawn

    A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived Lys-plasminogen proteins. … Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase

  3. Drug

    Acrivastine

    go.drugbank.com/drugs/DB09488
    Approved

    Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. … Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D.

    Mixtures: Semprex-D, Semprex DCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Mitoquinone

    go.drugbank.com/drugs/DB05063
    Investigational

    Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes … -- where they accumulate up to a thousand fold.

  5. Drug

    Diosmetin

    go.drugbank.com/drugs/DB11259
    Approved

    Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits [A27231]. … Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities [A27231]. It also acts as a weak TrkB receptor agonist [A27230].

    Synonyms: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone, 3',5,7-trihydroxy-4'-methoxyflavoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Abitesartan

    go.drugbank.com/drugs/DB19863
    Experimental

    Abitesartan is a small molecule drug. The usage of the INN stem '-sartan' in the name indicates that Abitesartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). … Abitesartan has a monoisotopic molecular weight of 461.24 Da.

  7. Drug

    WP-1301

    go.drugbank.com/drugs/DB17702
    Experimental

    WP1301 is a synthetic peptide derived from hFVIII. It binds to an MHC class II molecule and is recognized by a Factor VIII-specific T cell.[L46138]

  8. Drug

    IONIS-FGFR4Rx

    go.drugbank.com/drugs/DB16198
    Investigational

    IONIS-FGFR4Rx is under investigation in clinical trial NCT02476019 (A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients).

  9. Drug

    Ex vivo expanded autologous human corneal epithelial cells containing stem cells

    go.drugbank.com/drugs/DB18660
    ApprovedWithdrawn

    Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.[L48375]

    Synonyms: Ex vivo expanded autologous human corneal epithelial cells containing stem cells
  10. Drug

    Gonyautoxin II

    go.drugbank.com/drugs/DB19186
    Investigational

    Gonyautoxin II is under investigation in clinical trial NCT04799041 (Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 1h,10h-pyrrolo(1,2-c)purine-9,10,10-triol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, 9-(hydrogen sulfate), (3as-(3a.alpha.,4.alpha.,9.beta.,10ar*))- 11.alpha., Gonyautoxin 2