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Displaying results 5391 - 5400 of 8697 in total
  1. Drug

    TC-5231

    go.drugbank.com/drugs/DB05333
    Experimental

    TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder).

  2. Drug

    Almotriptan

    go.drugbank.com/drugs/DB00918
    Approved

    Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  3. Drug

    Enrofloxacin

    go.drugbank.com/drugs/DB11404
    InvestigationalVet approved

    Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. … Due to the identification of fluoroquinolone-resistant strains of _Campylobacter_, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat flocks of poultry.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inhibitors
  4. Drug

    AN0128

    go.drugbank.com/drugs/DB05054
    Investigational

    AN0128 has broad spectrum activity against a wide variety of Gram positive bacteria, including many that are known skin colonizers. … AN0128 is a good candidate for a topical antibiotic and is currently being developed by Anacor as a novel therapeutic for acne and atopic dermatitis.

  5. Drug

    Rocapuldencel-T

    go.drugbank.com/drugs/DB17588
    Investigational

    Rocapuldencel-T is an autologous dendritic cell immunotherapy that was investigated in NCT02662634 (A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer

  6. Drug

    AVXS-301

    go.drugbank.com/drugs/DB17943
    Experimental

    It is being investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).[L47077] … AVXS-301 consists of an adeno-associated virus serotype 9 (AAV9) designed to express the superoxide dismutase 1 (SOD1) gene.

  7. Drug

    XC221

    go.drugbank.com/drugs/DB16503
    Investigational

    XC221 was investigated in clinical trials to treat patients with respiratory infections, including influenza, COVID-19, and other acute viral upper respiratory infections.

    Categories: Experimental Unapproved Treatments for COVID-19
  8. Drug

    Mosedipimod

    go.drugbank.com/drugs/DB12592
    Investigational

    Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.

    Categories: Experimental Unapproved Treatments for COVID-19
  9. Target

    Guanylyl cyclase C

    go.drugbank.com/bio_entities/BE0003502
    TargetHumans

    Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270).

    Synonyms: STA receptor, Heat-stable enterotoxin receptor
  10. Target

    Prohibitin-2

    go.drugbank.com/bio_entities/BE0009007
    TargetHumans

    Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcrip...

    Synonyms: B-cell receptor-associated protein BAP37, Repressor of estrogen receptor activity