Search
Suvorexant
go.drugbank.com/drugs/DB09034ApprovedInvestigationalSuvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: BELSOMRA® 15 MG, BELSOMRA® 10 MGKraurosis Vulvae
go.drugbank.com/conditions/DBCOND0114418Synonyms: Lichen sclerosus et atrophicus, Lichen sclerosus et atropicusDL-alpha tocopheryl acetate
go.drugbank.com/drugs/DB14477ApprovedMixtures: Vitamins A, C & E Cap., Folika-MGCategories: Vitamin ESaquinavir
go.drugbank.com/drugs/DB01232ApprovedInvestigationalIn 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a relatively benign adverse effect profile as compared … Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: BIOQUINAVIR ® CAPSULAS 200MG, SAQUINAVIR 500 MG TABLETAS.Ciprofibrate
go.drugbank.com/drugs/DB09064ApprovedInvestigationalWithdrawnProducts: GIABRI® 100 MG TABLETAS, HIPERLIPEN ® 100 MG TABLETARimonabant
go.drugbank.com/drugs/DB06155ApprovedWithdrawnThis decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression. … It was rejected for approval for use in the United States.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: ACOMPLIA ® COMPRIMIDOS RECUBIERTOS20 MGCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. … medium that is then processed and purified for use as a pharmaceutical agent.
Products: BENEFIX 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET, BENEFIX 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADETTetrabenazine
go.drugbank.com/drugs/DB04844ApprovedIt is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008. … A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders.
Synonyms: 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one, 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSapropterin
go.drugbank.com/drugs/DB00360ApprovedInvestigationalIt is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of … Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingSynonyms: (6R)-L-erythro-tetrahydrobiopterin, 6R-L-5,6,7,8-tetrahydrobiopterinVilazodone
go.drugbank.com/drugs/DB06684ApprovedInvestigationalVilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. … Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AgonistsProducts: ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET, ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET