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RAPA-501-Allo
go.drugbank.com/drugs/DB15890InvestigationalRAPA-501-ALLO is composed of T-cells extracted from healthy volunteers; these cells are then reprogrammed _ex vivo_ in a process that involves de-differentiation and re-differentiation.[L16483]
Pemlimogene merolisbac
go.drugbank.com/drugs/DB16286InvestigationalPemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab … Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).
Synonyms: Recombinant live-attenuated double-deleted (ladd) strain of listeria monocytogenes (lm .delta.acta/.delta.inlb) expressing a fusion protein comprising the n-terminal 100 amino acids of the lm acta proteinEC-0652
go.drugbank.com/drugs/DB15340ExperimentalEC-0652 is under investigation in clinical trial NCT02202447 (Phase 1 of EC1169 In Patients With Recurrent MCRPC).
D-Serine
go.drugbank.com/drugs/DB03929ApprovedInvestigationalWithdrawnA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
GLB-001
go.drugbank.com/drugs/DB32795InvestigationalGLB-001 is a orally bioavailable molecular glue degrader targeting casein kinase 1 alpha (CK1a).
Tamibarotene
go.drugbank.com/drugs/DB04942InvestigationalTamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical trials in the United States.
AI-128
go.drugbank.com/drugs/DB05841ExperimentalAI-128 is the first human demonstration of sustained release drug administration in the lung. … AI-128 consists of slowly dissolving microspheres designed to control where drug particles go in the lung and how quickly they release their drug.
Bopindolol
go.drugbank.com/drugs/DB08807ExperimentalBopindolol (INN) is an ester prodrug for the beta blocker [pindolol].
Milataxel
go.drugbank.com/drugs/DB12334InvestigationalMilataxel has been used in trials studying the treatment of Mesothelioma.
Cethromycin
go.drugbank.com/drugs/DB06419InvestigationalCethromycin is a 3-keto (ketolide) derivative of erythromycin A with an 11,12-carbamate group and an O-6-linked aromatic ring system.